Reactome | EFNBs [plasma membrane]

EFNBs [plasma membrane]

Stable Identifier

R-RNO-3928378

Type

Set [DefinedSet]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

Ephrin B subclass

Locations in the PathwayBrowser

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Developmental Biology (Rattus norvegicus)

- Nervous system development (Rattus norvegicus)
  - Axon guidance (Rattus norvegicus)
    - EPH-Ephrin signaling (Rattus norvegicus)
      - EPH receptors autophosphorylate (Rattus norvegicus)
        
        EPH-ephrin oligomers [plasma membrane] (Rattus norvegicus)
        
        EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
      - EPH-ephrin mediated repulsion of cells (Rattus norvegicus)
        
        MMP2,9 cleave EPHB (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        SFKs phosphorylate VAV2,3 (Rattus norvegicus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        VAV exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPHs bind VAV2,3 (Rattus norvegicus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Rattus norvegicus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
      - EPH:EFN dimers tetramerise (Rattus norvegicus)
        
        EPH-EFN dimers [plasma membrane] (Rattus norvegicus)
        
        EPHB:EFNB dimers [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
      - EPH:EFN tetramers oligomerise (Rattus norvegicus)
        
        EPH-EFN dimers [plasma membrane] (Rattus norvegicus)
        
        EPHB:EFNB dimers [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPH-ephrin oligomers [plasma membrane] (Rattus norvegicus)
        
        EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
      - EPHB-mediated forward signaling (Rattus norvegicus)
        
        CDC42 and PIP2 bind WASL, activating it (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHB phosphorylates TIAM1 (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1 [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHB2 binds KALRN (Rattus norvegicus)
        
        EFNBs:p-EPHBs:KALRN [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHB:NMDAR binds TIAM1 (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        KALRN exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
        
        EFNBs:p-EPHBs:KALRN [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        N-WASP binds ARP2/3 and G-actin (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        Ras:GTP binds p120-RasGAP (Rattus norvegicus)
        
        p-EPHBs:EFNBs:RASA1 [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:RASA1 [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        Recruitment of p190RhoGEF to p-FAK (Rattus norvegicus)
        
        EFNBs:p-EPHBs:p-Y397-PTK2 [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:p-Y397-PTK2:ARHGEF28 [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:p-Y397-PTK2 [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPHB phosphorylates SDC2 (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1 [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:SFKs [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Rattus norvegicus)
        
        p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:RASA1 [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs:RASA1 [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Rattus norvegicus)
        
        EFNBs:p-EPHBs:p-Y397-PTK2:ARHGEF28 [plasma membrane] (Rattus norvegicus)
        
        EFNBs:p-EPHBs:p-Y397-PTK2 [plasma membrane] (Rattus norvegicus)
        
        p-EPHB:EFNB oligomers [plasma membrane] (Rattus norvegicus)
        
        p-EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
      - EPHBs bind EFNBs (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
      - Ephrin signaling (Rattus norvegicus)
        
        EFNBs bind SDCBP (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs:SDCBP [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs bind SFKs (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs:SRC,FYN [plasma membrane] (Rattus norvegicus)
        
        EPHBs:EFNBs [plasma membrane] (Rattus norvegicus)
        
        EFNBs [plasma membrane] (Rattus norvegicus)

Participants

members

Participates

as an input of

EPHBs bind EFNBs (Rattus norvegicus)

as an output of

MMP2,9 cleave EPHB (Rattus norvegicus)

as a component of

Inferred From

EFNBs [plasma membrane] (Homo sapiens)

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