Reactome | Lpar3 [plasma membrane]

Lpar3 [plasma membrane]

Stable Identifier

R-RNO-419379

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

LPAR3, Q8K5E0

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        Lpar3 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        Lpar3 [plasma membrane] (Rattus norvegicus)
    - G alpha (q) signalling events (Rattus norvegicus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        Lpar3 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        Lpar3 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Lysosphingolipid and LPA receptors (Rattus norvegicus)
        
        LPA-binding receptors bind LPA (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        Lpar3 [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
        
        LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)
        
        Lpar3 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q8K5E0

Gene Names

Lpar3

Reference Genes

BioGPS Gene:66025 Lpar3

ENSEMBL:ENSRNOG00000015260

ENSEMBL:ENSRNOG00000064204

KEGG Gene (Rattus norvegicus):66025 Lpar3

Monarch:66025 Lpar3

NCBI Gene:66025 Lpar3

Reference Transcript

Participates

as a member of

LPAR1,2,3,5 [plasma membrane] (Rattus norvegicus)

Inferred From

LPAR3 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_008759745.1, XP_017446585.1, XP_006233532.1, XP_017446586.1, NP_076459.1, XP_006233531.1, XP_008759744.1

ZINC - Substances

LPAR3_RAT

ZINC target

Q8K5E0

PRO

Q8K5E0

ZINC - Predictions - Purchasable

LPAR3_RAT

RGD

620565