NCAM1 cis-homophilic interaction

Stable Identifier
R-RNO-420387
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
NCAM1 cis-homophilic interaction

NCAM1 located on the cell membrane can participate in parallel cis and antiparallel trans-homophilic interactions. The cis-interaction is mediated by reciprocal IgI-IgII interactions: the IgI domain of one NCAM1 molecule interacts with the IgII domain of a second.

Literature References
PubMed ID Title Journal Year
14527396 Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion

Soroka, V, Kolkova, K, Kastrup, JS, Diederichs, K, Breed, J, Kiselyov, VV, Poulsen, FM, Larsen, IK, Welte, W, Berezin, V, Bock, E, Kasper, C

Structure 2003
Participants
Orthologous Events
Authored
Reviewed
Created
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