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PAK3 [cytosol]
Stable Identifier
R-RNO-428457
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
Q62829
Locations in the PathwayBrowser
Expand all
Developmental Biology (Rattus norvegicus)
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
EPH-Ephrin signaling (Rattus norvegicus)
Ephrin signaling (Rattus norvegicus)
PAK binds RAC and bPIX (Rattus norvegicus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Rattus norvegicus)
PAK1/3, 2 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1/3, 2 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAKs autophosphorylate (Rattus norvegicus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Rattus norvegicus)
PAK1/3, 2 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1/3, 2 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Semaphorin interactions (Rattus norvegicus)
Sema3A PAK dependent Axon repulsion (Rattus norvegicus)
Activation of PAK by Rac1 (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1,2,3 dimer [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Autophosphorylation of PAK (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Costimulation by the CD28 family (Rattus norvegicus)
CD28 co-stimulation (Rattus norvegicus)
CD28 dependent Vav1 pathway (Rattus norvegicus)
Activation of PAKs by RAC1 and CDC42 (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1,2,3 dimer [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
TCR signaling (Rattus norvegicus)
Generation of second messenger molecules (Rattus norvegicus)
NCK binds PAK (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
p-SLP-76:NCK:PAK [cytosol] (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
C-type lectin receptors (CLRs) (Rattus norvegicus)
CD209 (DC-SIGN) signaling (Rattus norvegicus)
PAK phosphorylates p21 RAF1 on S338 (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK6/MAPK4 signaling (Rattus norvegicus)
Activation of PAKs by RAC1 and CDC42 (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1,2,3 dimer [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Autophosphorylation of PAK1,2,3 (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
VEGFR2 mediated vascular permeability (Rattus norvegicus)
PAK1-3 autophosphorylates (Rattus norvegicus)
PAK1,2,3 dimer [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1-3 dimer disassociates (Rattus norvegicus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Rattus norvegicus)
PAK1,2,3 dimer [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
RAC1 binds PAK1-3 (Rattus norvegicus)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Rattus norvegicus)
PAK1,2,3 dimer [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK1,2,3 dimer [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases activate PAKs (Rattus norvegicus)
Autophosphorylation of PAK1,2,3 (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
RAC1 and CDC42 activate PAK3 (Rattus norvegicus)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
RHO GTPase cycle (Rattus norvegicus)
RAC1 GTPase cycle (Rattus norvegicus)
RAC1 binds effectors at the plasma membrane (Rattus norvegicus)
RAC1 effectors [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
RAC1:GTP:RAC1 effectors [plasma membrane] (Rattus norvegicus)
RAC1 effectors [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
RHOU GTPase cycle (Rattus norvegicus)
RHOU binds effectors at the plasma membrane (Rattus norvegicus)
RHOU effectors [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
RHOU:GTP:RHOU effectors [plasma membrane] (Rattus norvegicus)
RHOU effectors [cytosol] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
PAK3 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q62829
Reference Genes
BioGPS Gene:29433
ENSEMBL:ENSRNOG00000004676
ENSEMBL:ENSRNOG00000004676.8
ENSEMBL:ENSRNOG00055025067
ENSEMBL:ENSRNOG00060019042
ENSEMBL:ENSRNOG00065026400
KEGG Gene (Rattus norvegicus):29433
Monarch:29433
NCBI Gene:29433
Reference Transcript
RefSeq:NM_019210.1
RefSeq:XM_006257339.3
Other Identifiers
10937362
1368902_at
17876618
29433
5692938
5706820
5735272
5760596
5770558
5918893
5926553
5936640
5937484
5996242
6117542
6263558
6269970
6312625
6394776
6495247
6551649
6567189
6596304
A_44_P208304
GE1278171
GE20586
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0006468
GO:0016740
GO:0036211
GO:0140096
U33314_at
rc_AA997367_s_at
Participates
as a member of
PAK1/3, 2 [cytosol] (Rattus norvegicus)
PAK1,2,3 [cytosol] (Rattus norvegicus)
as an output of
RAC1 and CDC42 activate PAK3 (Rattus norvegicus)
as a component of
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Rattus norvegicus)
PAK3 dimer [cytosol] (Rattus norvegicus)
Other forms of this molecule
phospho-p-S154,T436-PAK3 [plasma membrane]
phospho-p-S154,T436-PAK3 [cytosol]
Inferred From
PAK3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_062083.1
,
XP_006257401.1
IntEnz
2.7.11.1
Ensembl
ENSRNOG00000004676
,
ENSRNOT00000006459
,
ENSRNOP00000006459
PRO
Q62829
RGD
3251
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