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NCOA1 [nucleoplasm]
Stable Identifier
R-RNO-442496
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
A0A8I6APA0
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Cytoprotection by HMOX1 (Rattus norvegicus)
Fatty acid ligands activate PPARA (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
PPARA:RXRA Coactivator complex [nucleoplasm] (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
Epigenetic regulation of gene expression (Rattus norvegicus)
Epigenetic regulation by WDR5-containing histone modifying complexes (Rattus norvegicus)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Rattus norvegicus)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Rattus norvegicus)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Rattus norvegicus)
Coactivators are recruited to liganded PPARG:RXRA heterodimer (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:ADIPOQ gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:AGPAT2 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:ANGPTL4 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:CD36 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:CEBPA gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:CIDEC gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:FABP4 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:LIPE gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:LPL gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:MGLL gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:PDK4 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:PEX11A gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:PLIN1 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:PLIN2 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:PLIN4 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:PNPLA2 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:PPARG gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated PPARG:RXRA:SCD gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated p-Y78,Y102-PPARG2:RXRA:ACSS3 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated p-Y78,Y102-PPARG2:RXRA:ELOVL5 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated p-Y78,Y102-PPARG2:RXRA:SCD5 gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Activated p-Y78,Y102-PPARG2:RXRA:THRSP gene:nucleosomes [nucleoplasm] (Rattus norvegicus)
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Endogenous sterols (Rattus norvegicus)
CYP7A1 7-hydroxylates CHOL (Rattus norvegicus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
CYP7B1 7-hydroxylates 25OH-CHOL (Rattus norvegicus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Recycling of bile acids and salts (Rattus norvegicus)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Rattus norvegicus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1,NCOA2,RXRA [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Rattus norvegicus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
CYP7B1 7-hydroxylates 25OH-CHOL (Rattus norvegicus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Rattus norvegicus)
27-hydroxycholesterol is 7alpha-hydroxylated (Rattus norvegicus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
CYP7A1 7-hydroxylates CHOL (Rattus norvegicus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Regulation of lipid metabolism by PPARalpha (Rattus norvegicus)
Fatty acid ligands activate PPARA (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
PPARA:RXRA Coactivator complex [nucleoplasm] (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
SUMOylation (Rattus norvegicus)
SUMO E3 ligases SUMOylate target proteins (Rattus norvegicus)
SUMOylation of transcription cofactors (Rattus norvegicus)
SUMOylation of NCOA1 with SUMO1 (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Estrogen-dependent gene expression (Rattus norvegicus)
Histone acetyltransferases are recruited to the TFF1 gene (Rattus norvegicus)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Rattus norvegicus)
histone acetyltransferases [nucleoplasm] (Rattus norvegicus)
NCOA1,NCOA3 [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
histone acetyltransferases [nucleoplasm] (Rattus norvegicus)
NCOA1,NCOA3 [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1 binds ESR1:estrogen:TGFA gene (Rattus norvegicus)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1 recruits EP300 to TGFA promoter (Rattus norvegicus)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
ESR1:estrogen:TFGA gene:NCOA1:EP300 [nucleoplasm] (Rattus norvegicus)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NR1H2 and NR1H3-mediated signaling (Rattus norvegicus)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Rattus norvegicus)
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Rattus norvegicus)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1 recruits EP300 to the ABCA1 promoter (Rattus norvegicus)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
NCOA1 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A8I6APA0
Reference Genes
ENSEMBL:ENSRNOG00000004068
UCSC:A0A8I6APA0
Participates
as an input of
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Rattus norvegicus)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Rattus norvegicus)
NCOA1 binds ESR1:estrogen:TGFA gene (Rattus norvegicus)
SUMOylation of NCOA1 with SUMO1 (Rattus norvegicus)
as a component of
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Rattus norvegicus)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Rattus norvegicus)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Rattus norvegicus)
as a member of
NCOA1,NCOA3 [nucleoplasm] (Rattus norvegicus)
NCOA1,NCOA2,RXRA [nucleoplasm] (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
as a candidate of
(NCOA1, NCOA2, NCOA3) [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
monoSUMO1-K732,K774-NCOA1 [nucleoplasm]
NCOA1 (868-1441) [nucleoplasm]
Inferred From
NCOA1 [nucleoplasm]
(Homo sapiens)
Cross References
GlyGen
A0A8I6APA0
RGD
1309046
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