Reactome | Hnrnpk [nucleoplasm]

Hnrnpk [nucleoplasm]

Stable Identifier

R-RNO-4570532

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

polySUMO2-K422-HNRNPK, P61980

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P61980

Gene Names

Hnrnpk

Reference Genes

BioGPS Gene:117282 Hnrnpk

ENSEMBL:ENSRNOG00000019113

KEGG Gene (Rattus norvegicus):117282 Hnrnpk

Monarch:117282 Hnrnpk

NCBI Gene:117282 Hnrnpk

UCSC:P61980 Hnrnpk

Reference Transcript

Participates

as an output of

CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Rattus norvegicus)

Other forms of this molecule

Hnrnpk [nucleoplasm]

Inferred From

polySUMO2-K422-HNRNPK [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (polySUMO2 [nucleoplasm]) at 422 (in Homo sapiens)

Coordinate

422

Modification

polySUMO2 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_476482.1, XP_006253616.1

PRO

P61980

RGD

71058

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00523 SRC	9	SRC [cytosol] (R-GGA-9628701) phospho-p-Y419-SRC [cytosol] (R-GGA-8964276) Src [cytosol] (R-GGA-3928468) MyrG-SRC [plasma membrane] (R-GGA-8876922) phospho-p-Y419-SRC [cytosol] (R-GGA-377592) phospho-MyrG,p-Y530-SRC [plasma membrane] (R-GGA-377598) SRC-1 [plasma membrane] (R-GGA-65043) phospho-MyrG-p-Y419-SRC [plasma membrane] (R-GGA-1810408) SRC-2 [cytosol] (R-GGA-191648)	0.544	2
UniProt:P06241 FYN	6	p-S21,Y420-FYN [cytosol] (R-HSA-5218745) p-Y531-FYN [cytosol] (R-HSA-391819) MyrG2-PalmC3,6-FYN [plasma membrane] (R-HSA-9606873) p-Y420-FYN [cytosol] (R-HSA-391821) MyrG-p-Y420-FYN [plasma membrane] (R-HSA-1810410) FYN [cytosol] (R-HSA-200917)	0.469	2
UniProt:P07948 LYN	7	MyrG2-PalmC3-LYN [lysosomal membrane] (R-HSA-9707903) MyrG2-PalmC3-LYN [endocytic vesicle membrane] (R-HSA-9705728) LYN [plasma membrane] (R-HSA-197943) p-Y397-LYN [cytosol] (R-HSA-8942608) p-Y397-LYN [plasma membrane] (R-HSA-2454229) MyrG2-PalmC3-LYN [plasma membrane] (R-HSA-9606875) LYN [cytosol] (R-HSA-354251)	0.469	2
UniProt:P13471	2	Rps14 [nucleoplasm] (R-RNO-6790669) Rps14 [cytosol] (R-RNO-72333)	0.462	2

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