Reactome | Tcf7l1 [nucleoplasm]

Tcf7l1 [nucleoplasm]

Stable Identifier

R-RNO-5228649

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

TCF7L1, A0A8I5ZT78

Locations in the PathwayBrowser

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Developmental Biology (Rattus norvegicus)

- MITF-M-regulated melanocyte development (Rattus norvegicus)
  - MITF-M-dependent gene expression (Rattus norvegicus)
    - Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Rattus norvegicus)
      - HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Rattus norvegicus)
        
        HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF [nucleoplasm] (Rattus norvegicus)
        
        Tcf7l1 [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Rattus norvegicus)
        
        TCF/LEF [nucleoplasm] (Rattus norvegicus)
        
        Tcf7l1 [nucleoplasm] (Rattus norvegicus)

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - Generic Transcription Pathway (Rattus norvegicus)
    - Transcriptional regulation by RUNX3 (Rattus norvegicus)
      - RUNX3 regulates WNT signaling (Rattus norvegicus)
        
        RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Rattus norvegicus)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        Tcf7l1 [nucleoplasm] (Rattus norvegicus)
        
        RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Rattus norvegicus)
        
        Tcf7l1 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I5ZT78

Gene Names

Tcf7l1

Reference Genes

BioGPS Gene:312451 Tcf7l1

ENSEMBL:ENSRNOG00000014753

ENSEMBL:ENSRNOG00000014753.8 Tcf7l1

Monarch:312451 Tcf7l1

NCBI Gene:312451 Tcf7l1

Reference Transcript

RefSeq:XM_006236674.3 Tcf7l1

Other Identifiers

10863258

10863275

10863277

1382558_at

1390283_at

17792323

17792342

312451

5631147

5740358

5748645

5762599

5809891

5854351

6051563

6112960

6131296

6233818

6296004

6381596

6426122

6451127

6498510

6515656

6557534

6579902

6595594

6615901

6713838

6724293

A_44_P377629

A_64_P013318

A_64_P013324

GE1100219

GO:0003677

GO:0005634

GO:0005654

GO:0005829

GO:0016055

GO:0023052

GO:0043226

GO:1990837

ILMN_1363479

PH_rn_0008432

PH_rn_0018928

rc_AA998085_at

rc_AI045720_at

Participates

as a candidate of

as a member of

TCF/LEF [nucleoplasm] (Rattus norvegicus)

Inferred From

TCF7L1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_006236736.1

Ensembl

ENSRNOG00000014753, ENSRNOT00000106765, ENSRNOP00000081559

RGD

1311671

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