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Erlec1 [endoplasmic reticulum quality control compartment]
Stable Identifier
R-RNO-5362354
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
endoplasmic reticulum quality control compartment
Synonyms
ERLEC1, D3ZF97
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Hedgehog (Rattus norvegicus)
Hedgehog ligand biogenesis (Rattus norvegicus)
C-terminal Hh fragments are bound by lectins (Rattus norvegicus)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Rattus norvegicus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
SYVN1 ubiquitinates Hh C-terminal fragments (Rattus norvegicus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Transport of small molecules (Rattus norvegicus)
ABC-family proteins mediated transport (Rattus norvegicus)
CFTR binds components of the ERAD machinery for ubiquitination and degradation (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Rattus norvegicus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Erlec1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D3ZF97
Gene Names
Erlec1
Reference Genes
BioGPS Gene:289874 Erlec1
ENSEMBL:ENSRNOG00000007283
ENSEMBL:ENSRNOG00000007283.7 Erlec1
KEGG Gene (Rattus norvegicus):289874 Erlec1
Monarch:289874 Erlec1
NCBI Gene:289874 Erlec1
Reference Transcript
RefSeq:NM_001106023.1 Erlec1
Other Identifiers
10778897
1373346_at
1395331_at
17696819
289874
5631966
5674984
5740586
5815947
5818812
5923519
6134637
6161322
6175471
6240595
6399209
6478832
6506283
6672568
6726305
A_42_P537516
A_44_P350843
A_44_P554377
GE18567
GO:0023052
GO:0030163
GO:0030433
GO:0030968
PH_rn_0015367
rc_AI009492_at
rc_AI029283_at
Participates
as a member of
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Inferred From
ERLEC1 [endoplasmic reticulum quality control compartment]
(Homo sapiens)
Cross References
RefSeq
NP_001099493.2
Ensembl
ENSRNOG00000007283
,
ENSRNOT00000050321
,
ENSRNOP00000043115
RGD
1306508
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