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OS9/ERLEC1 [endoplasmic reticulum quality control compartment]
Stable Identifier
R-RNO-5362377
Type
Set [DefinedSet]
Species
Rattus norvegicus
Compartment
endoplasmic reticulum membrane
,
endoplasmic reticulum quality control compartment
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Hedgehog (Rattus norvegicus)
Hedgehog ligand biogenesis (Rattus norvegicus)
C-terminal Hh fragments are bound by lectins (Rattus norvegicus)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Rattus norvegicus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
SYVN1 ubiquitinates Hh C-terminal fragments (Rattus norvegicus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Transport of small molecules (Rattus norvegicus)
ABC-family proteins mediated transport (Rattus norvegicus)
CFTR binds components of the ERAD machinery for ubiquitination and degradation (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Rattus norvegicus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Rattus norvegicus)
Participants
members
Erlec1 [endoplasmic reticulum quality control compartment]
(Rattus norvegicus)
OS9 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Participates
as an output of
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Rattus norvegicus)
as an input of
C-terminal Hh fragments are bound by lectins (Rattus norvegicus)
as a component of
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Rattus norvegicus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
Inferred From
OS9/ERLEC1 [endoplasmic reticulum quality control compartment]
(Homo sapiens)
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