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SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
Stable Identifier
R-RNO-5362378
Type
Complex
Species
Rattus norvegicus
Compartment
endoplasmic reticulum membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Hedgehog (Rattus norvegicus)
Hedgehog ligand biogenesis (Rattus norvegicus)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Rattus norvegicus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
SYVN1 ubiquitinates Hh C-terminal fragments (Rattus norvegicus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Rattus norvegicus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Derl2 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Sel1l [endoplasmic reticulum membrane]
(Rattus norvegicus)
SYVN1 dimer [endoplasmic reticulum membrane]
(Rattus norvegicus)
VCP hexamer [cytosol]
(Rattus norvegicus)
Participates
as an output of
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Rattus norvegicus)
as an input of
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Rattus norvegicus)
as a component of
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Rattus norvegicus)
Inferred From
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane]
(Homo sapiens)
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