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phospho-Stat3 [cytosol]
Stable Identifier
R-RNO-539048
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
p-Y705,S727-STAT3, P52631
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-6 family signaling (Rattus norvegicus)
Interleukin-6 signaling (Rattus norvegicus)
Serine phosphorylation of STATs (Rattus norvegicus)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3 [plasma membrane] (Rattus norvegicus)
Tyrosine/serine phosphorylated STAT1, STAT3 [cytosol] (Rattus norvegicus)
phospho-Stat3 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ALK (Rattus norvegicus)
STAT3 is phosphorylated downstream of active ALK (Rattus norvegicus)
phospho-Stat3 [cytosol] (Rattus norvegicus)
p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Rattus norvegicus)
p-Y705,S727-STAT3 dimer [cytosol] (Rattus norvegicus)
phospho-Stat3 [cytosol] (Rattus norvegicus)
p-Y705,S727-STAT3 dimerizes (Rattus norvegicus)
p-Y705,S727-STAT3 dimer [cytosol] (Rattus norvegicus)
phospho-Stat3 [cytosol] (Rattus norvegicus)
phospho-Stat3 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P52631 Stat3
Gene Names
Stat3
Chain
initiator methionine:1, chain:2-770
Reference Genes
BioGPS Gene:25125 Stat3
ENSEMBL:ENSRNOG00000019742 Stat3
KEGG Gene (Rattus norvegicus):25125 Stat3
Monarch:25125 Stat3
NCBI Gene:25125 Stat3
Reference Transcript
RefSeq:NM_012747.2 Stat3
Other Identifiers
10747506
1370224_at
1371781_at
17661537
25125
5658612
5697002
5818860
5845715
5862208
5895490
5965620
6004312
6057185
6072088
6095813
6120614
6151646
6299125
6445188
6474533
6499876
6560310
6566097
6577375
6628532
6642802
6699796
6704922
6724793
6730579
A_44_P381881
A_44_P787936
GE1203572
GE13732
GE19939
GO:0000003
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001103
GO:0001228
GO:0001659
GO:0001754
GO:0002376
GO:0003674
GO:0003677
GO:0003700
GO:0003723
GO:0004879
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0005975
GO:0006091
GO:0006355
GO:0006366
GO:0006412
GO:0006606
GO:0006810
GO:0006913
GO:0006914
GO:0006950
GO:0006954
GO:0007049
GO:0007165
GO:0008134
GO:0008150
GO:0008283
GO:0008285
GO:0009056
GO:0009058
GO:0010507
GO:0010628
GO:0015031
GO:0016310
GO:0019827
GO:0019899
GO:0019901
GO:0019903
GO:0019953
GO:0030154
GO:0030335
GO:0030522
GO:0031490
GO:0032355
GO:0032731
GO:0032733
GO:0032757
GO:0032760
GO:0032870
GO:0032991
GO:0033210
GO:0034641
GO:0040007
GO:0040011
GO:0040014
GO:0042592
GO:0042593
GO:0042755
GO:0042789
GO:0042802
GO:0042803
GO:0043226
GO:0043565
GO:0044281
GO:0044320
GO:0044321
GO:0045648
GO:0045747
GO:0045766
GO:0045820
GO:0045893
GO:0045944
GO:0046983
GO:0048646
GO:0048708
GO:0048856
GO:0048870
GO:0051726
GO:0060019
GO:0060259
GO:0060396
GO:0060397
GO:0070102
GO:0070878
GO:0072538
GO:0072540
GO:0090575
GO:0097009
GO:1900017
GO:1902895
GO:1904685
GO:1905564
GO:1905618
GO:2000635
GO:2000637
GO:2000737
GO:2001223
ILMN_1373442
PH_rn_0006495
rc_AI008865_s_at
rc_AI012356_at
rc_AI236828_s_at
Participates
as an input of
p-Y705,S727-STAT3 dimerizes (Rattus norvegicus)
as a component of
p-Y705,S727-STAT3 dimer [cytosol] (Rattus norvegicus)
as an output of
STAT3 is phosphorylated downstream of active ALK (Rattus norvegicus)
as a member of
Tyrosine/serine phosphorylated STAT1, STAT3 [cytosol] (Rattus norvegicus)
Other forms of this molecule
phospho-Stat3 [nucleoplasm]
phospho-Stat3 [cytosol]
phospho-Stat3 [nucleoplasm]
phospho-Stat3 [nucleoplasm]
phospho-Stat3 [nucleoplasm]
Phospho-STAT3 [cytosol]
phospho-Stat3 [cytosol]
phospho-Stat3 [cytosol]
Signal transducer and activator of transcription 3 [cytosol]
phospho-Stat3 [nucleoplasm]
Inferred From
p-Y705,S727-STAT3 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 727
Coordinate
727
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 705 (in Homo sapiens)
Coordinate
705
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_036879.1
Ensembl
ENSRNOT00000026760
,
ENSRNOG00000019742
,
ENSRNOP00000026760
PRO
P52631
RGD
3772
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O13097 EFNB1
0.524
4
UniProt:Q9NRF2 SH2B1
1
SH2B1 [cytosol]
(R-HSA-997253)
0.471
2
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