Reactome | FEN1 [nucleoplasm]

FEN1 [nucleoplasm]

Stable Identifier

R-RNO-54745

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

Q5XIP6

Locations in the PathwayBrowser

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Cell Cycle (Rattus norvegicus)

- Cell Cycle, Mitotic (Rattus norvegicus)
  - S Phase (Rattus norvegicus)
    - Synthesis of DNA (Rattus norvegicus)
      - DNA strand elongation (Rattus norvegicus)
        
        Lagging Strand Synthesis (Rattus norvegicus)
        
        Processive synthesis on the lagging strand (Rattus norvegicus)
        
        Removal of the Flap Intermediate (Rattus norvegicus)
        
        Removal of remaining Flap (Rattus norvegicus)
        
        FEN1 [nucleoplasm] (Rattus norvegicus)
- Chromosome Maintenance (Rattus norvegicus)
  - Telomere Maintenance (Rattus norvegicus)
    - Extension of Telomeres (Rattus norvegicus)
      - Telomere C-strand (Lagging Strand) Synthesis (Rattus norvegicus)
        
        Processive synthesis on the C-strand of the telomere (Rattus norvegicus)
        
        Removal of the Flap Intermediate from the C-strand (Rattus norvegicus)
        
        Removal of remaining Flap from the C-strand (Rattus norvegicus)
        
        FEN1 [nucleoplasm] (Rattus norvegicus)

DNA Replication (Rattus norvegicus)

- Synthesis of DNA (Rattus norvegicus)
  - DNA strand elongation (Rattus norvegicus)
    - Lagging Strand Synthesis (Rattus norvegicus)
      - Processive synthesis on the lagging strand (Rattus norvegicus)
        
        Removal of the Flap Intermediate (Rattus norvegicus)
        
        Removal of remaining Flap (Rattus norvegicus)
        
        FEN1 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q5XIP6

Reference Genes

BioGPS Gene:84490

ENSEMBL:ENSRNOG00000020531

ENSEMBL:ENSRNOG00055017939

ENSEMBL:ENSRNOG00060030600

ENSEMBL:ENSRNOG00065033963

KEGG:rno:84490

Monarch:84490

NCBI Gene:84490

UCSC:Q5XIP6

Reference Transcript

Other Identifiers

10728644

1367983_at

17640419

5838662

6172533

6325938

84490

A_42_P664520

A_44_P418824

GE1293652

GE13547

GO:0000781

GO:0003677

GO:0003824

GO:0004518

GO:0004523

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005739

GO:0006260

GO:0008409

GO:0016787

GO:0016788

GO:0017108

GO:0032991

GO:0043137

GO:0043226

GO:0045876

GO:0048256

GO:0090304

GO:0140097

GO:0140098

ILMN_1353164

PH_rn_0006895

rc_AA819793_at

Participates

as an input of

as a component of

as an output of

FEN1 cleaves displaced ssDNA flaps during MMEJ (Rattus norvegicus)

Inferred From

FEN1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_008758467.1, XP_006231135.1, NP_445882.1, XP_008758468.1, XP_006231136.1

ENSEMBL

ENSRNOT00000027842, ENSRNOP00000027842, ENSRNOT00000104683, ENSRNOP00000078106, ENSRNOT00000106648, ENSRNOP00000081266

PRO

Q5XIP6

RGD

621821