Reactome | PARP1,PARP2 dimers [nucleoplasm]

PARP1,PARP2 dimers [nucleoplasm]

Stable Identifier

R-RNO-5649884

Type

Complex

Species

Rattus norvegicus

Compartment

nucleoplasm

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 2 PARP1,PARP2 [nucleoplasm] (Rattus norvegicus)

Participates

as an output of

PARG dePARylates PARP1,PARP2 (Rattus norvegicus)

as an input of

PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Rattus norvegicus)
PARP1 or PARP2 binds DDB2 at GG-NER site (Rattus norvegicus)
PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Rattus norvegicus)

as a component of

PARP1,PARP2:FEN1:POLB:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Rattus norvegicus)
PARP1,PARP2:FEN1:POLB:SSB(3'poly-dNMP-displaced 5'ddRP-FLAP)-dsDNA [nucleoplasm] (Rattus norvegicus)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:UV-DDB:PARP1,PARP2 [nucleoplasm] (Rattus norvegicus)
Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Rattus norvegicus)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Rattus norvegicus)

Inferred From

PARP1,PARP2 dimers [nucleoplasm] (Homo sapiens)

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