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phospho-Ksr1 [cytosol]
Stable Identifier
R-RNO-5672656
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
p-S311,Y602 KSR1, A0A8I5ZQW6
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
MAP2K and MAPK activation (Rattus norvegicus)
Dissociation of RAS:RAF complex (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
Dual mechanism MAPK inhibitors bind MAPKs (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
MAP2Ks and MAPKs bind to the activated RAF complex (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
MAP2Ks phosphorylate MAPKs (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
RAF phosphorylates MAP2K dimer (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAF:YWHAB dimer [cytosol] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Rattus norvegicus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
Negative regulation of MAPK pathway (Rattus norvegicus)
PEBP1 binds activated RAF1 (Rattus norvegicus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Rattus norvegicus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
PP2A dephosphorylates RAF1 (Rattus norvegicus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
PP5 dephosphorylates RAF1 S338 (Rattus norvegicus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
RAF activation (Rattus norvegicus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Rattus norvegicus)
'activator' RAF:YWHAB dimer [cytosol] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAF:YWHAB dimer [cytosol] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
Phosphorylation of RAF (Rattus norvegicus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAF:YWHAB dimer [cytosol] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAF:YWHAB dimer [cytosol] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAF:YWHAB dimer [cytosol] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
Raf dimer inhibitors bind RAF heterodimers (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAF:YWHAB dimer [cytosol] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Rattus norvegicus)
'activator' RAF:YWHAB dimer [cytosol] (Rattus norvegicus)
'activator' RAFs [cytosol] (Rattus norvegicus)
phospho-Ksr1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A8I5ZQW6
Gene Names
Ksr1
Reference Genes
ENSEMBL:ENSRNOG00000012818
ENSEMBL:ENSRNOG00000012818.8 Ksr1
Reference Transcript
RefSeq:XM_017597667.1 Ksr1
Other Identifiers
10745303
108348076
17659003
5658988
5711574
5714319
5785440
5842053
5867285
5953606
5958279
6184660
6199857
6202886
6239982
6309728
6338153
6344412
6355092
6369282
6369651
6380402
6433964
6475019
6537596
6548022
6593365
6612797
6654843
A_44_P368427
GO:0003824
GO:0004672
GO:0005078
GO:0005524
GO:0006468
GO:0007265
GO:0016740
GO:0019901
GO:0019933
GO:0023052
GO:0031434
GO:0036211
GO:0042127
GO:0043410
GO:0051087
GO:0051879
GO:0060090
GO:0071889
GO:0140096
ILMN_1371154
Participates
as a candidate of
'activator' RAFs [cytosol] (Rattus norvegicus)
Other forms of this molecule
phospho-Ksr1 [cytosol]
Ksr1 [cytosol]
phospho-Ksr1 [cytosol]
phospho-Ksr1 [plasma membrane]
Inferred From
p-S311,Y602 KSR1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 311 (in Homo sapiens)
Coordinate
311
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 602 (in Homo sapiens)
Coordinate
602
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_017453156.1
Ensembl
ENSRNOP00000080543
,
ENSRNOT00000110577
,
ENSRNOG00000012818
RGD
1308105
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