Reactome | (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle]

(Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle]

Stable Identifier

R-RNO-5689724

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

COPII-coated ER to Golgi transport vesicle

Synonyms

P80067

Locations in the PathwayBrowser

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Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Asparagine N-linked glycosylation (Rattus norvegicus)
    - Transport to the Golgi and subsequent modification (Rattus norvegicus)
      - ER to Golgi Anterograde Transport (Rattus norvegicus)
        
        COPII-mediated vesicle transport (Rattus norvegicus)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Rattus norvegicus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        CSNK1D phosphorylates SEC23 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        Nucleotide exchange on RAB1 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        Vesicle budding (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)

Vesicle-mediated transport (Rattus norvegicus)

- Membrane Trafficking (Rattus norvegicus)
  - ER to Golgi Anterograde Transport (Rattus norvegicus)
    - COPII-mediated vesicle transport (Rattus norvegicus)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Rattus norvegicus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
      - COPII coat binds TRAPPCII and RAB1:GDP (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
      - CSNK1D phosphorylates SEC23 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
      - Nucleotide exchange on RAB1 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
      - Vesicle budding (Rattus norvegicus)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Rattus norvegicus)
        
        glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)
        
        (Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P80067

Reference Genes

BioGPS Gene:25423

ENSEMBL:ENSRNOG00000016496

KEGG:rno:25423

Monarch:25423

NCBI Gene:25423

UCSC:P80067

Reference Transcript

RefSeq:NM_017097.1

Other Identifiers

10708521

1368280_at

1374778_at

17618127

25423

5629240

5754777

5757243

5812837

5818350

6004399

6042605

6174900

6245900

6357257

6496533

6546208

6620840

6668763

A_43_P11819

D90404_at

D90404_g_at

GE20338

GE21631

GO:0001913

GO:0002376

GO:0003824

GO:0004252

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0006508

GO:0006954

GO:0008234

GO:0012501

GO:0016505

GO:0016787

GO:0023052

GO:0031642

GO:0043226

GO:0043231

GO:0048856

GO:0050877

GO:0098772

GO:0140096

GO:1903980

GO:2001235

ILMN_1359951

PH_rn_0010870

rc_AA926360_at

Participates

as a member of

glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Rattus norvegicus)

Other forms of this molecule

CTSC(25-134) [lysosomal lumen]

(Glc)3(GlcNAc)2(Man)9-CTSC [endoplasmic reticulum-Golgi intermediate compartment membrane]

(Glc)3(GlcNAc)2(Man)9-CTSC [endoplasmic reticulum lumen]

CTSC(25-134) [extracellular region]

CTSC(25-134) [azurophil granule lumen]

Inferred From

(Glc)3(GlcNAc)2(Man)9-CTSC [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

ENSEMBL

ENSRNOT00000022342, ENSRNOP00000022342, ENSRNOG00000016496

IntEnz

3.4.14.1

PRO

P80067

GlyGen

P80067

RGD

2445

PDB

1JQP

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