Reactome | Arrb2 [cytosol]

Arrb2 [cytosol]

Stable Identifier

R-RNO-6783000

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

PolyUb-ARRB2, P29067

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Deubiquitination (Rattus norvegicus)
    - Ub-specific processing proteases (Rattus norvegicus)
      - USP33 deubiquitinates CCP110,ARRB (Rattus norvegicus)
        
        USP33:PolyUb-CCP110,PolyUb-ARRB1,PolyUb-ARRB2 [cytosol] (Rattus norvegicus)
        
        PolyUb-CCP110, PolyUb-ARRB2,(PolyUb-ARRB1) [cytosol] (Rattus norvegicus)
        
        Arrb2 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P29067

Gene Names

Arrb2

Reference Genes

BioGPS Gene:25388 Arrb2

ENSEMBL:ENSRNOG00000019308

KEGG Gene (Rattus norvegicus):25388 Arrb2

Monarch:25388 Arrb2

NCBI Gene:25388 Arrb2

UCSC:P29067 Arrb2

Reference Transcript

RefSeq:NM_012911.1 Arrb2

Other Identifiers

10735205

1370265_at

17647752

17756756

25388

5681608

5717651

5794024

5896837

5919323

6042245

6072139

6116464

6143136

6151309

6194558

6248256

6287221

6331317

6341351

6342882

6389479

6408748

6658514

6692098

A_44_P379214

GE1240200

GE20051

GO:0001664

GO:0001932

GO:0001933

GO:0001934

GO:0002031

GO:0002032

GO:0002092

GO:0002376

GO:0005102

GO:0005515

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005768

GO:0005829

GO:0005886

GO:0005905

GO:0006351

GO:0006355

GO:0006366

GO:0006897

GO:0007005

GO:0007165

GO:0007179

GO:0007186

GO:0007420

GO:0007628

GO:0008277

GO:0009968

GO:0010628

GO:0012501

GO:0014069

GO:0015031

GO:0016020

GO:0016192

GO:0016323

GO:0016567

GO:0019899

GO:0019904

GO:0022414

GO:0023052

GO:0030139

GO:0030154

GO:0030163

GO:0031397

GO:0031410

GO:0031623

GO:0031625

GO:0031691

GO:0031692

GO:0031701

GO:0031702

GO:0031748

GO:0031762

GO:0031826

GO:0031859

GO:0032088

GO:0032226

GO:0032691

GO:0032695

GO:0032715

GO:0032720

GO:0032967

GO:0033138

GO:0034122

GO:0034260

GO:0034392

GO:0036211

GO:0042699

GO:0042802

GO:0043154

GO:0043161

GO:0043197

GO:0043226

GO:0043422

GO:0043524

GO:0044877

GO:0045211

GO:0045953

GO:0048856

GO:0048870

GO:0050731

GO:0050877

GO:0050965

GO:0051019

GO:0051897

GO:0051928

GO:0060326

GO:0070374

GO:0071889

GO:0090201

GO:0098542

GO:1904037

GO:1990763

GO:2000573

GO:2000727

ILMN_1370634

M91590_at

M91590_g_at

rc_AA964003_s_at

rc_AI013765_s_at

rc_AI136065_s_at

Participates

as a member of

PolyUb-CCP110, PolyUb-ARRB2,(PolyUb-ARRB1) [cytosol] (Rattus norvegicus)

Other forms of this molecule

Arrb2 [cytosol]

Inferred From

PolyUb-ARRB2 [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine (PolyUb [cytosol]) at unknown position

Modification

PolyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_037043.1

Ensembl

ENSRNOP00000026207, ENSRNOT00000026207, ENSRNOG00000019308

PRO

P29067

RGD

2157

PDB

6K3F

HMDB Protein

HMDBP14510

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00987 MDM2	11	PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472) monoSUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) MDM2 [plasma membrane] (R-HSA-416843) MDM2 [endocytic vesicle membrane] (R-HSA-416849) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) MDM2 [nucleoplasm] (R-HSA-69486) MDM2 [cytosol] (R-HSA-198644) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669)	0.631	4
UniProt:P31749 AKT1	13	p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308-AKT1 [cytosol] (R-HSA-198634) AKT1 [cytosol] (R-HSA-58252) AKT1 [plasma membrane] (R-HSA-199416) p-S473-AKT1 [plasma membrane] (R-HSA-377265) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357)	0.524	2
UniProt:P53667 LIMK1	3	p-S,T508-LIMK1 [cytosol] (R-HSA-419610) p-T508-LIMK1 [cytosol] (R-HSA-399816) LIMK1 [cytosol] (R-HSA-397785)	0.524	2
UniProt:P29067	2	Arrb2 [cytosol] (R-RNO-6783000) Arrb2 [cytosol] (R-RNO-416464)	0.512	3
UniProt:P49187	3	MAPK10 [cytosol] (R-RNO-450352) phospho-p-T221,Y223-MAPK10 [cytosol] (R-RNO-450214) phospho-p-T221,Y223-MAPK10 [nucleoplasm] (R-RNO-450311)	0.508	3