Reactome | Shank2 [cytosol]

Shank2 [cytosol]

Stable Identifier

R-RNO-6794265

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

SHANK2, Q9QX74

Locations in the PathwayBrowser

Expand all

Neuronal System (Rattus norvegicus)

- Protein-protein interactions at synapses (Rattus norvegicus)
  - Neurexins and neuroligins (Rattus norvegicus)
    - ABP1 binds SHANK proteins (Rattus norvegicus)
      - NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Rattus norvegicus)
        
        SHANK1,2,3 [cytosol] (Rattus norvegicus)
        
        Shank2 [cytosol] (Rattus norvegicus)
      - NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3:DBNL [cytosol] (Rattus norvegicus)
        
        NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Rattus norvegicus)
        
        SHANK1,2,3 [cytosol] (Rattus norvegicus)
        
        Shank2 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q9QX74

Gene Names

Shank2

Reference Genes

BioGPS Gene:171093 Shank2

ENSEMBL:ENSRNOG00000047651

ENSEMBL:ENSRNOG00000050206

ENSEMBL:ENSRNOG00000050206 Shank2

KEGG Gene (Rattus norvegicus):171093 Shank2

Monarch:171093 Shank2

NCBI Gene:171093 Shank2

UCSC:Q9QX74 Shank2

Reference Transcript

Other Identifiers

10712580

1369776_a_at

1369777_a_at

171093

17622593

5637018

5644332

5731858

5753746

5754613

5760013

5819339

5849658

5865065

5943273

5966618

5976638

6004920

6054667

6130839

6134246

6198374

6229716

6237814

6251076

6257886

6261933

6323479

6358693

6361923

6385546

6420823

6433242

6474327

6512547

6520443

6550457

6573299

6648994

AF060116_at

A_44_P247745

A_44_P299282

A_64_P144253

GE1181293

GE1231274

GO:0001750

GO:0001917

GO:0005198

GO:0005515

GO:0005737

GO:0005856

GO:0005883

GO:0005886

GO:0005929

GO:0007416

GO:0007584

GO:0007612

GO:0007613

GO:0008284

GO:0008306

GO:0008344

GO:0009410

GO:0014069

GO:0016020

GO:0016324

GO:0017124

GO:0023052

GO:0030160

GO:0030426

GO:0030534

GO:0031526

GO:0032279

GO:0034330

GO:0035176

GO:0035255

GO:0035331

GO:0035640

GO:0042995

GO:0043005

GO:0043025

GO:0043197

GO:0043226

GO:0045202

GO:0045211

GO:0048786

GO:0048856

GO:0050808

GO:0050877

GO:0051968

GO:0060090

GO:0060170

GO:0060291

GO:0060292

GO:0071625

GO:0098686

GO:0098919

GO:0098978

GO:0099175

GO:0099562

GO:0120025

ILMN_1375384

ILMN_1375908

ILMN_1376750

ILMN_1650300

PH_rn_0018626

rc_AI071947_s_at

Participates

as a member of

SHANK1,2,3 [cytosol] (Rattus norvegicus)

Inferred From

SHANK2 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_017444213.1, NP_958738.1, NP_001004133.1, NP_597684.1, NP_597685.1

Ensembl

ENSRNOT00000092386, ENSRNOP00000075839, ENSRNOG00000050206, ENSRNOP00000075919, ENSRNOT00000092516, ENSRNOT00000075078, ENSRNOP00000065891

PRO

Q9QX74

RGD

628772

PDB

6CPJ

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.658	3