Reactome | Shank1 [cytosol]

Shank1 [cytosol]

Stable Identifier

R-RNO-6794274

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

SHANK1, Q9WV48

Locations in the PathwayBrowser

Expand all

Neuronal System (Rattus norvegicus)

- Protein-protein interactions at synapses (Rattus norvegicus)
  - Neurexins and neuroligins (Rattus norvegicus)
    - ABP1 binds SHANK proteins (Rattus norvegicus)
      - NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Rattus norvegicus)
        
        SHANK1,2,3 [cytosol] (Rattus norvegicus)
        
        Shank1 [cytosol] (Rattus norvegicus)
      - NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3:DBNL [cytosol] (Rattus norvegicus)
        
        NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3 [plasma membrane] (Rattus norvegicus)
        
        SHANK1,2,3 [cytosol] (Rattus norvegicus)
        
        Shank1 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q9WV48 Shank1

Gene Names

Shank1

Chain

chain:1-2167

Reference Genes

BioGPS Gene:78957 Shank1

KEGG:rno:78957 Shank1

Monarch:78957 Shank1

NCBI Gene:78957 Shank1

UCSC:Q9WV48 Shank1

Reference Transcript

Other Identifiers

10706515

1368445_at

1387192_at

17616006

5624639

5629919

5675674

5681641

5691190

5700816

5709263

5764536

5791059

5855336

5859183

5877410

5906571

5920126

5983866

6043179

6059275

6068253

6071090

6196809

6275013

6297666

6306858

6332088

6383433

6427720

6437065

6451034

6475803

6504403

6516442

6517052

6578572

6586938

6619169

6666705

6704579

6732459

78957

AF102855_at

A_44_P289284

A_64_P059993

A_64_P102990

A_64_P102996

GE13404

GO:0005198

GO:0005515

GO:0005886

GO:0007010

GO:0007616

GO:0008306

GO:0014069

GO:0016020

GO:0023052

GO:0030154

GO:0030160

GO:0030425

GO:0030534

GO:0032232

GO:0034330

GO:0035176

GO:0035255

GO:0035418

GO:0042048

GO:0043005

GO:0043197

GO:0043226

GO:0045211

GO:0046959

GO:0048856

GO:0050804

GO:0050877

GO:0050885

GO:0050894

GO:0060013

GO:0060076

GO:0060090

GO:0060997

GO:0071625

GO:0098685

GO:0098919

GO:0098978

GO:2000463

ILMN_1373188

PH_rn_0011700

Participates

as a member of

SHANK1,2,3 [cytosol] (Rattus norvegicus)

Other forms of this molecule

Shank1 [cytosol]

Inferred From

SHANK1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSRNOT00000092327, ENSRNOT00000044257, ENSRNOG00000019207, ENSRNOP00000084101, ENSRNOP00000039860, ENSRNOP00000026100, ENSRNOT00000104599, ENSRNOT00000026100, ENSRNOP00000075838

PRO

Q9WV48

GlyGen

Q9WV48

RGD

621011

PDB

3QJN, 7A9B, 1Q3O, 3QJM, 1Q3P, 3L4F

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P97836 Dlgap1	2	Gkap1 [plasma membrane] (R-RNO-6794237) Dlgap1 [plasma membrane] (R-RNO-6794239)	0.745	7
UniProt:Q61625 GRID2			0.602	5
UniProt:Q9Z214-2 HOMER1			0.591	4
UniProt:Q9ES28-2 ARHGEF7			0.581	6
UniProt:P31016 Dlg4	3	Dlg4 [plasma membrane] (R-RNO-9612601) Dlg4 [endocytic vesicle membrane] (R-RNO-416847) Dlg4 [cytosol] (R-RNO-6794248)	0.564	3
UniProt:Q9EQL9 Sharpin	1	Sharpin [cytosol] (R-RNO-6794270)	0.543	7
UniProt:P21575 Dnm1	4	DNM1 [cytosol] (R-RNO-2213182) Dynamin 1 [plasma membrane] (R-RNO-941853) DNM1 [lysosomal membrane] (R-RNO-196150) DNM1 [plasma membrane] (R-RNO-177488)	0.524	2
UniProt:P39052 Dnm2	5	DNM2 [Golgi membrane] (R-RNO-2980842) DNM2 [endocytic vesicle membrane] (R-RNO-2029000) Dnm2 [cytosol] (R-RNO-9619847) DNM2 [lysosomal membrane] (R-RNO-2980840) Dynamin-2 [plasma membrane] (R-RNO-941852)	0.524	2
UniProt:P18654 Rps6ka3	5	phospho-p-4S,T231,T365-RPS6KA3 [nucleoplasm] (R-MMU-199830) p-S227-Rps6ka3 [nucleoplasm] (R-MMU-9620027) Rps6ka3 [nucleoplasm] (R-MMU-9620028) phospho-p-S227,T365,S369,S386,T577,T737-RPS6KA3 [cytosol] (R-MMU-9619872) phospho-p-S227,T365,S369,S386,T577,T737-RPS6KA3 [nucleoplasm] (R-MMU-444286)	0.508	2
UniProt:P97836-5 DLGAP1			0.508	2