Reactome | Anapc16 [cytosol]

Anapc16 [cytosol]

Stable Identifier

R-RNO-6805138

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

ANAPC16, D3ZDN9

Locations in the PathwayBrowser

Expand all

Cell Cycle (Rattus norvegicus)

- Cell Cycle Checkpoints (Rattus norvegicus)
  - Mitotic Spindle Checkpoint (Rattus norvegicus)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Rattus norvegicus)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Rattus norvegicus)
        
        Binding of the MCC complex to the APC/C complex (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
- Cell Cycle, Mitotic (Rattus norvegicus)
  - M Phase (Rattus norvegicus)
    - Mitotic Metaphase and Anaphase (Rattus norvegicus)
      - Mitotic Anaphase (Rattus norvegicus)
        
        Separation of Sister Chromatids (Rattus norvegicus)
        
        Association of Securin with Cdc20:APC/C complex (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Degradation of multiubiquitinated Securin (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
  - Regulation of mitotic cell cycle (Rattus norvegicus)
    - APC/C-mediated degradation of cell cycle proteins (Rattus norvegicus)
      - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Rattus norvegicus)
        
        Association of cell cycle proteins with the APC/C:Cdh1 complex (Rattus norvegicus)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Degradation of multiubiquitinated cell cycle proteins (Rattus norvegicus)
        
        multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Rattus norvegicus)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
      - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Rattus norvegicus)
        
        APC/C:Cdc20 mediated degradation of mitotic proteins (Rattus norvegicus)
        
        APC/C:Cdc20 mediated degradation of Cyclin B (Rattus norvegicus)
        
        Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Degradation of multiubiquitinated Cyclin B (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Rattus norvegicus)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Rattus norvegicus)
        
        Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        APC/C:Cdc20 mediated degradation of Securin (Rattus norvegicus)
        
        Association of Securin with Cdc20:APC/C complex (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Degradation of multiubiquitinated Securin (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
        
        CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Rattus norvegicus)
        
        APC-Cdc20 mediated degradation of Nek2A (Rattus norvegicus)
        
        Association of Nek2A with MCC:APC/C (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Degradation of multiubiquitinated Nek2A (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Multiubiquitinated Nek2A [cytosol] (Rattus norvegicus)
        
        Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Multiubiquitination of Nek2A (Rattus norvegicus)
        
        Multiubiquitinated Nek2A [cytosol] (Rattus norvegicus)
        
        Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Rattus norvegicus)
        
        Association of Cyclin A with the APC/C (Rattus norvegicus)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Degradation multiubiquitinated Cyclin A (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Rattus norvegicus)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
      - Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Rattus norvegicus)
        
        Association of Cdh1 with the APC/C (Rattus norvegicus)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        Dissociation of Cdc20 from APC/C complex (Rattus norvegicus)
        
        CDC20:p-APC/C [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
      - Regulation of APC/C activators between G1/S and early anaphase (Rattus norvegicus)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Rattus norvegicus)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Rattus norvegicus)
        
        Binding of the MCC complex to the APC/C complex (Rattus norvegicus)
        
        MCC:APC/C complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)
  - S Phase (Rattus norvegicus)
    - Synthesis of DNA (Rattus norvegicus)
      - Switching of origins to a post-replicative state (Rattus norvegicus)
        
        CDK-mediated phosphorylation and removal of Cdc6 (Rattus norvegicus)
        
        Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Rattus norvegicus)
        
        phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
        
        phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
        
        Anapc16 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZDN9

Gene Names

Anapc16

Reference Genes

ENSEMBL:ENSRNOG00000000576

ENSEMBL:ENSRNOG00000000576.7 Anapc16

UCSC:D3ZDN9 Anapc16

Other Identifiers

100360936

10832927

1388957_at

17758316

5761350

6112865

6113441

6158473

6448035

6577174

6653547

A_44_P728960

GE12615

GO:0005634

GO:0005680

GO:0016567

GO:0036211

GO:0043226

ILMN_1373588

PH_rn_0022019

rc_AA891790_at

Participates

as a component of

phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)

Other forms of this molecule

Anapc16 [nucleoplasm]

Inferred From

ANAPC16 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSRNOG00000000576, ENSRNOP00000000702, ENSRNOT00000000702

RGD

2321124

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