Reactome | HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane]

HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane]

Stable Identifier

R-RNO-6806977

Type

Complex

Species

Rattus norvegicus

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 2 HGF dimer:p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (Rattus norvegicus)

Participates

as an output of

RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Rattus norvegicus)
MET phosphorylates STAT3 (Rattus norvegicus)
MET dimers autophosphorylate (Rattus norvegicus)

as an input of

PTPN1 and PTPN2 dephosphorylate MET (Rattus norvegicus)
PTPRJ dephosphorylates MET (Rattus norvegicus)
PTK2 binds activated MET (Rattus norvegicus)
MET binds TNS4 (Rattus norvegicus)
MET binds TNS3 (Rattus norvegicus)
MET binds RANBP10 (Rattus norvegicus)
MUC20 binds MET and inhibits GRB2 binding (Rattus norvegicus)
Activated MET binds GAB1 and GRB2 (Rattus norvegicus)
Activated MET binds GAB1 (Rattus norvegicus)
STAT3 binds activated MET receptor (Rattus norvegicus)
MET binds SHC1-2 (Rattus norvegicus)
Activated MET recruits GRB2-1:SOS1 (Rattus norvegicus)
Activated MET binds RANBP9 and SOS1 (Rattus norvegicus)

as a component of

HGF:p-4Y-MET dimer:GRB2:p-Y-CBL [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2:CBL [plasma membrane] (Rattus norvegicus)
HGF:p-Y1003,4Y-MET dimer:CBL [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:PTK2 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:TNS4:ITGB1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:TNS3 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:STAT3 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:SHC1-2 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y MET dimer:MUC20 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:RANBP10 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:p-Y317-SHC1-2 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:RANBP9:SOS1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] (Rattus norvegicus)

as a member of

HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer) [plasma membrane] (Rattus norvegicus)

Inferred From

HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane] (Homo sapiens)