Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
phospho-Polr2a [nucleoplasm]
Stable Identifier
R-RNO-6810226
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
p-S5,S7(CTD)-POLR2A, D4A5A6
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
RNA polymerase II transcribes snRNA genes (Rattus norvegicus)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Rattus norvegicus)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Rattus norvegicus)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Rattus norvegicus)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Rattus norvegicus)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Rattus norvegicus)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
phospho-Polr2a [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D4A5A6
Gene Names
Polr2a
Reference Genes
BioGPS Gene:363633 Polr2a
ENSEMBL:ENSRNOG00000028834
ENSEMBL:ENSRNOG00000028834.6 Polr2a
KEGG Gene (Rattus norvegicus):363633 Polr2a
Monarch:363633 Polr2a
NCBI Gene:363633 Polr2a
UCSC:D4A5A6 Polr2a
Reference Transcript
RefSeq:XM_001079162.5 Polr2a
RefSeq:XM_343922.7 Polr2a
Other Identifiers
10744182
1388808_at
17657828
363633
5658268
5666589
5670727
5672016
5676592
5764501
5786954
5832141
5890639
5905951
5916076
5945266
5979095
6082082
6230057
6270082
6279599
6336772
6367523
6385697
6404856
6421675
6470679
6473912
6545246
6606844
6613405
6642072
6655881
6674757
6683075
6686948
6711485
6727301
6728160
A_44_P253468
A_44_P340884
GE1156586
GO:0000791
GO:0001046
GO:0003677
GO:0003824
GO:0003899
GO:0005634
GO:0005654
GO:0005694
GO:0006351
GO:0006366
GO:0016740
GO:0043226
GO:0140098
ILMN_1372495
PH_rn_0017285
PH_rn_0021080
X59608exon_at
rc_AA819317_at
rc_AI103719_at
Participates
as a component of
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
phospho-Polr2a [nucleoplasm]
phospho-Polr2a [nucleoplasm]
phospho-Polr2a [nucleoplasm]
phospho-Polr2a [nucleoplasm]
Polr2a [nucleoplasm]
phospho-Polr2a [nucleoplasm]
Inferred From
p-S5,S7(CTD)-POLR2A [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1843 (in Homo sapiens)
Coordinate
1843
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1845 (in Homo sapiens)
Coordinate
1845
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1850 (in Homo sapiens)
Coordinate
1850
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1857 (in Homo sapiens)
Coordinate
1857
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1864 (in Homo sapiens)
Coordinate
1864
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1871 (in Homo sapiens)
Coordinate
1871
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1878 (in Homo sapiens)
Coordinate
1878
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1892 (in Homo sapiens)
Coordinate
1892
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1899 (in Homo sapiens)
Coordinate
1899
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1906 (in Homo sapiens)
Coordinate
1906
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1913 (in Homo sapiens)
Coordinate
1913
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1920 (in Homo sapiens)
Coordinate
1920
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1927 (in Homo sapiens)
Coordinate
1927
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1934 (in Homo sapiens)
Coordinate
1934
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_001079162.1
,
XP_343923.3
Ensembl
ENSRNOG00000028834
,
ENSRNOT00000068013
,
ENSRNOP00000061492
RGD
1587326
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text