Reactome | Rprd1b [nucleoplasm]

Rprd1b [nucleoplasm]

Stable Identifier

R-RNO-6814894

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

RPRD1B, B5DEK0

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Rattus norvegicus)

- RNA Polymerase II Transcription (Rattus norvegicus)
  - RNA polymerase II transcribes snRNA genes (Rattus norvegicus)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
    - Integrator complex processes the 3' end of snRNA (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Rattus norvegicus)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
    - RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Rattus norvegicus)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Rattus norvegicus)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)
      - RPRD1A,B:RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        RPRD1A,B [nucleoplasm] (Rattus norvegicus)
        
        Rprd1b [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:B5DEK0

Gene Names

Rprd1b

Reference Genes

BioGPS Gene:311591 Rprd1b

ENSEMBL:ENSRNOG00000012923

ENSEMBL:ENSRNOG00000012923.8 Rprd1b

KEGG Gene (Rattus norvegicus):311591 Rprd1b

Monarch:311591 Rprd1b

NCBI Gene:311591 Rprd1b

Reference Transcript

RefSeq:NM_001098727.1 Rprd1b

Other Identifiers

10841669

17768314

311591

5624387

5673835

6008167

6112277

6128483

6165266

6420728

6476487

6615784

6725660

A_64_P028406

GO:0000993

GO:0001111

GO:0005634

GO:0005654

GO:0006351

GO:0006355

GO:0008284

GO:0010564

GO:0042802

GO:0043226

GO:0045944

GO:0097550

ILMN_1651080

rc_AA850624_at

Participates

as a member of

RPRD1A,B [nucleoplasm] (Rattus norvegicus)

Inferred From

RPRD1B [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001092197.1

Ensembl

ENSRNOT00000017265, ENSRNOG00000012923, ENSRNOP00000017265

RGD

1304782

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