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Mdm2 [nucleoplasm]
Stable Identifier
R-RNO-69486
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
MDM2, A0A0G2JVC1
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
Regulation of TP53 Activity (Rattus norvegicus)
Regulation of TP53 Expression and Degradation (Rattus norvegicus)
Regulation of TP53 Degradation (Rattus norvegicus)
MDM2 translocates to the cytosol (Rattus norvegicus)
Mdm2 [nucleoplasm] (Rattus norvegicus)
PP2A-PP2R5C dephosphorylates MDM2 (Rattus norvegicus)
Mdm2 [nucleoplasm] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Deubiquitination (Rattus norvegicus)
Ub-specific processing proteases (Rattus norvegicus)
USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Rattus norvegicus)
USP7:TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] (Rattus norvegicus)
TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] (Rattus norvegicus)
Mdm2 [nucleoplasm] (Rattus norvegicus)
SUMOylation (Rattus norvegicus)
SUMO E3 ligases SUMOylate target proteins (Rattus norvegicus)
SUMOylation of ubiquitinylation proteins (Rattus norvegicus)
PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Rattus norvegicus)
Mdm2 [nucleoplasm] (Rattus norvegicus)
RANBP2 SUMOylates MDM2 with SUMO1 (Rattus norvegicus)
Mdm2 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A0G2JVC1
Gene Names
Mdm2
Reference Genes
BioGPS Gene:314856 Mdm2
ENSEMBL:ENSRNOG00000006304
ENSEMBL:ENSRNOG00000006304.8 Mdm2
Monarch:314856 Mdm2
NCBI Gene:314856 Mdm2
Reference Transcript
RefSeq:XM_006241383.2 Mdm2
RefSeq:XM_006241382.1 Mdm2
Other Identifiers
10902564
1383288_at
1383485_at
1384427_at
17836020
314856
5692726
5791899
5915045
6108596
6150437
6178586
6218132
6242309
6330283
6358230
6369573
6527698
6568748
6589842
AA108308_s_at
AA875509_at
A_44_P634946
GE1249606
GE1265548
GO:0000122
GO:0000278
GO:0001568
GO:0001974
GO:0002027
GO:0002039
GO:0003013
GO:0003170
GO:0003181
GO:0003203
GO:0003281
GO:0003283
GO:0003723
GO:0004842
GO:0005515
GO:0005622
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006357
GO:0006511
GO:0006886
GO:0006913
GO:0006915
GO:0006977
GO:0007089
GO:0007507
GO:0008097
GO:0008270
GO:0009410
GO:0009636
GO:0010039
GO:0010468
GO:0010628
GO:0010629
GO:0010955
GO:0010977
GO:0012501
GO:0016567
GO:0016604
GO:0016740
GO:0016874
GO:0016925
GO:0017053
GO:0019789
GO:0019899
GO:0019904
GO:0023052
GO:0030154
GO:0030163
GO:0031625
GO:0031648
GO:0032026
GO:0032436
GO:0032991
GO:0033612
GO:0034504
GO:0036211
GO:0042176
GO:0042220
GO:0042802
GO:0042975
GO:0043021
GO:0043066
GO:0043130
GO:0043154
GO:0043226
GO:0043278
GO:0043518
GO:0045184
GO:0045202
GO:0045472
GO:0045787
GO:0045892
GO:0045931
GO:0046677
GO:0046827
GO:0046872
GO:0047485
GO:0048545
GO:0048856
GO:0048870
GO:0051149
GO:0051603
GO:0051604
GO:0051726
GO:0051865
GO:0060411
GO:0061630
GO:0061663
GO:0065003
GO:0065008
GO:0070301
GO:0071236
GO:0071301
GO:0071310
GO:0071312
GO:0071363
GO:0071375
GO:0071391
GO:0071407
GO:0071456
GO:0071480
GO:0071494
GO:0072717
GO:0097718
GO:0140096
GO:1901797
GO:1902254
GO:1904404
GO:1904707
GO:1904754
GO:1990000
GO:1990785
ILMN_1364670
PH_rn_0007193
rc_AA849796_at
rc_AI639488_at
Participates
as a member of
TP53,MDM2,MDM4,FOXO4,PTEN [nucleoplasm] (Rattus norvegicus)
as an input of
PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Rattus norvegicus)
RANBP2 SUMOylates MDM2 with SUMO1 (Rattus norvegicus)
MDM2 translocates to the cytosol (Rattus norvegicus)
as an output of
PP2A-PP2R5C dephosphorylates MDM2 (Rattus norvegicus)
Other forms of this molecule
Mdm2 [nucleoplasm]
Mdm2 [nucleoplasm]
Mdm2 [plasma membrane]
Mdm2 [endocytic vesicle membrane]
phospho-Mdm2 [nucleoplasm]
phospho-Mdm2 [nucleoplasm]
phospho-Mdm2 [nucleoplasm]
Mdm2 [cytosol]
phospho-Mdm2 [cytosol]
phospho-Mdm2 [nucleoplasm]
Inferred From
MDM2 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_006241445.1
,
XP_006241444.1
Ensembl
ENSRNOT00000086116
,
ENSRNOP00000069425
,
ENSRNOG00000006304
RGD
1305332
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