Reactome | Hnrnpk [nucleoplasm]

Hnrnpk [nucleoplasm]

Stable Identifier

R-RNO-71945

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

HNRNPK, P61980

Locations in the PathwayBrowser

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Metabolism of RNA (Rattus norvegicus)

- Processing of Capped Intron-Containing Pre-mRNA (Rattus norvegicus)
  - Formation of pre-mRNPs (Rattus norvegicus)
    - Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
      - shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
      - Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
  - mRNA Splicing (Rattus norvegicus)
    - mRNA Splicing - Major Pathway (Rattus norvegicus)
      - Formation of the Spliceosomal B complex (Rattus norvegicus)
        
        Spliceosomal B complex [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal Pre-B complex [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal C complex containing intron lariat (Rattus norvegicus)
        
        Spliceosomal B* complex [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal C complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal C* complex (Rattus norvegicus)
        
        Spliceosomal C complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal C* complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal E complex (Rattus norvegicus)
        
        Spliceosomal E complex [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal P complex and exon ligation (Rattus norvegicus)
        
        Spliceosomal C* complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal P complex [nucleoplasm] (Rattus norvegicus)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)
        
        Hnrnpk [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P61980

Gene Names

Hnrnpk

Reference Genes

BioGPS Gene:117282 Hnrnpk

ENSEMBL:ENSRNOG00000019113

KEGG:rno:117282 Hnrnpk

Monarch:117282 Hnrnpk

NCBI Gene:117282 Hnrnpk

UCSC:P61980 Hnrnpk

Reference Transcript

Participates

as an input of

CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Rattus norvegicus)

as a member of

shuttling HNRNPs [nucleoplasm] (Rattus norvegicus)

Other forms of this molecule

Hnrnpk [nucleoplasm]

Inferred From

HNRNPK [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_006253616.1, NP_476482.1

PRO

P61980

GlyGen

P61980

RGD

71058

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00523 SRC	9	SRC-2 [cytosol] (R-GGA-191648) phospho-MyrG-p-Y419-SRC [plasma membrane] (R-GGA-1810408) SRC-1 [plasma membrane] (R-GGA-65043) phospho-MyrG,p-Y530-SRC [plasma membrane] (R-GGA-377598) phospho-p-Y419-SRC [cytosol] (R-GGA-377592) MyrG-SRC [plasma membrane] (R-GGA-8876922) Src [cytosol] (R-GGA-3928468) phospho-p-Y419-SRC [cytosol] (R-GGA-8964276) SRC [cytosol] (R-GGA-9628701)	0.544	2
UniProt:P06241 FYN	6	FYN [cytosol] (R-HSA-200917) MyrG-p-Y420-FYN [plasma membrane] (R-HSA-1810410) p-Y420-FYN [cytosol] (R-HSA-391821) MyrG2-PalmC3,6-FYN [plasma membrane] (R-HSA-9606873) p-Y531-FYN [cytosol] (R-HSA-391819) p-S21,Y420-FYN [cytosol] (R-HSA-5218745)	0.469	2
UniProt:P07948 LYN	7	LYN [cytosol] (R-HSA-354251) MyrG2-PalmC3-LYN [plasma membrane] (R-HSA-9606875) p-Y397-LYN [plasma membrane] (R-HSA-2454229) p-Y397-LYN [cytosol] (R-HSA-8942608) LYN [plasma membrane] (R-HSA-197943) MyrG2-PalmC3-LYN [endocytic vesicle membrane] (R-HSA-9705728) MyrG2-PalmC3-LYN [lysosomal membrane] (R-HSA-9707903)	0.469	2
UniProt:P13471	2	Rps14 [nucleoplasm] (R-RNO-6790669) Rps14 [cytosol] (R-RNO-72333)	0.462	2