Reactome | Srsf7 [nucleoplasm]

Srsf7 [nucleoplasm]

Stable Identifier

R-RNO-72029

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

SRSF7, A0A8I6AFZ5

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Rattus norvegicus)

- Processing of Capped Intron-Containing Pre-mRNA (Rattus norvegicus)
  - Formation of pre-mRNPs (Rattus norvegicus)
    - Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
      - shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
      - Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
  - Transport of Mature Transcript to Cytoplasm (Rattus norvegicus)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Rattus norvegicus)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Rattus norvegicus)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Rattus norvegicus)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
  - mRNA 3'-end processing (Rattus norvegicus)
    - mRNA Polyadenylation (Rattus norvegicus)
      - CPA complex components dissociate from polyadenylated pre-mRNA (distal 3'UTR PAS) (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - CPA complex components dissociate from polyadenylated pre-mRNA (intronic PAS) (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - CPA complex components dissociate from polyadenylated pre-mRNA (proximal 3'UTR PAS) (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated, polyadenylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - Core CPA complex binds capped pre-mRNA (Rattus norvegicus)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Rattus norvegicus)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - PP1 dephosphorylates RNA Pol II (Rattus norvegicus)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - RBBP6 activates CPSF complex (Rattus norvegicus)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - Recruitment of other CPA components to pre-mRNA-bound CPA core (Rattus norvegicus)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
  - mRNA Splicing (Rattus norvegicus)
    - mRNA Splicing - Major Pathway (Rattus norvegicus)
      - Formation of the Spliceosomal B* complex (Rattus norvegicus)
        
        Spliceosomal B* complex [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal Bact complex [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal C complex containing intron lariat (Rattus norvegicus)
        
        Spliceosomal B* complex [nucleoplasm] (Rattus norvegicus)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal C complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal C* complex (Rattus norvegicus)
        
        Spliceosomal C complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal C* complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - Formation of the Spliceosomal P complex and exon ligation (Rattus norvegicus)
        
        Spliceosomal C* complex [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        Spliceosomal P complex [nucleoplasm] (Rattus norvegicus)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Rattus norvegicus)
        
        Spliceosomal P complex [nucleoplasm] (Rattus norvegicus)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Rattus norvegicus)
        
        Alternative Splicing Factors [nucleoplasm] (Rattus norvegicus)
        
        shuttling SRSFs [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
    - mRNA Splicing - Minor Pathway (Rattus norvegicus)
      - ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Rattus norvegicus)
        
        ATAC C Complex [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        post exon ligation complex [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Rattus norvegicus)
        
        ATAC C Complex [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - Formation of AT-AC B Complex (Rattus norvegicus)
        
        ATAC A Complex [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        ATAC B Complex [nucleoplasm] (Rattus norvegicus)
        
        ATAC A Complex [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
      - Formation of AT-AC C complex (Rattus norvegicus)
        
        ATAC B Complex [nucleoplasm] (Rattus norvegicus)
        
        ATAC A Complex [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)
        
        ATAC C Complex [nucleoplasm] (Rattus norvegicus)
        
        Srsf7 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A8I6AFZ5

Gene Names

Srsf7

Reference Genes

BioGPS Gene:362687 Srsf7

ENSEMBL:ENSRNOG00000027360

KEGG:rno:362687 Srsf7

Monarch:362687 Srsf7

NCBI Gene:362687 Srsf7

UCSC:A0A8I6AFZ5 Srsf7

Reference Transcript

RefSeq:NM_001039035.2 Srsf7

Other Identifiers

10887981

1380391_at

1389337_at

17819714

362687

5633937

5635307

5671392

5675877

5683864

5688124

5710368

5798553

5802328

5880876

5903407

6038165

6075745

6078671

6101752

6296358

6322007

6347219

6384604

6426888

6450749

6509566

6604628

6713828

A_44_P151264

A_44_P253310

A_64_P015911

GE1221391

GE12892

GO:0003676

GO:0003723

GO:0005654

GO:0008270

GO:0008380

GO:0019904

GO:0048025

GO:1990830

PH_rn_0000643

PH_rn_0019123

rc_AA946032_at

rc_AI171267_at

rc_AI230724_at

Participates

as a component of

as a member of

shuttling SRSFs [nucleoplasm] (Rattus norvegicus)

Inferred From

SRSF7 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001034124.2

ENSEMBL

ENSRNOT00000097127, ENSRNOP00000091604, ENSRNOG00000027360

RGD

1307425

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