Reactome | Rps16 [cytosol]

Rps16 [cytosol]

Stable Identifier

R-RNO-72337

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

RPS16, P62250

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Rattus norvegicus)

- Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Rattus norvegicus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)
- rRNA processing (Rattus norvegicus)
  - rRNA processing in the nucleus and cytosol (Rattus norvegicus)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Rattus norvegicus)
      - 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Rps16 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P62250

Gene Names

Rps16

Reference Genes

BioGPS Gene:140655 Rps16

ENSEMBL:ENSRNOG00000019578

ENSEMBL:ENSRNOG00000031439

KEGG:rno:140655 Rps16

Monarch:140655 Rps16

NCBI Gene:140655 Rps16

UCSC:P62250 Rps16

Reference Transcript

RefSeq:NM_001169146.1 Rps16

Other Identifiers

10705511

1371318_at

140655

17614858

5719772

5779398

5807108

5885999

5991003

6020463

6256648

6479046

6488135

6529494

6698767

6718753

A_42_P544648

A_64_P068858

GE1163435

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0022626

GO:1990904

ILMN_1371004

PH_rn_0018161

X17665cds_s_at

rc_AI009810_at

rc_AI230338_at

Participates

as a component of

Other forms of this molecule

Rps16 [nucleoplasm]

Inferred From

RPS16 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001162617.1

ENSEMBL

ENSRNOT00000026576, ENSRNOP00000026576, ENSRNOG00000019578

PRO

P62250

RGD

621031

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