Reactome | Cyld [cytosol]

Cyld [cytosol]

Stable Identifier

R-RNO-741420

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

CYLD, Q66H62

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q66H62

Gene Names

Cyld

Reference Genes

BioGPS Gene:312937 Cyld

ENSEMBL:ENSRNOG00000014048

KEGG:rno:312937 Cyld

Monarch:312937 Cyld

NCBI Gene:312937 Cyld

UCSC:Q66H62 Cyld

Reference Transcript

RefSeq:XM_063278090.1 Cyld
RefSeq:XM_063278085.1 Cyld
RefSeq:XM_063278084.1 Cyld
RefSeq:XM_063278092.1 Cyld
RefSeq:XM_063278091.1 Cyld
RefSeq:XM_063278093.1 Cyld
RefSeq:XM_063278087.1 Cyld
RefSeq:XM_063278088.1 Cyld
RefSeq:NM_001017380.1 Cyld
RefSeq:XM_063278086.1 Cyld
RefSeq:XM_063278094.1 Cyld

Participates

as a component of

CYLD:K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG [cytosol] (Rattus norvegicus)
CYLD:OPTN:polyUb-RIPK1:TNFR1 complex [plasma membrane] (Rattus norvegicus)
MIB2:CYLD:UBE2D2 [cytosol] (Rattus norvegicus)
CYLD:SPATA2:LUBAC [cytosol] (Rattus norvegicus)

as an input of

OPTN recruits CYLD to the TNFR1 complex (Rattus norvegicus)
CHUK, IKBKB phosphorylate CYLD at S418 (Rattus norvegicus)
MIB2 binds CYLD (Rattus norvegicus)

as a member of

RIPK1 deubiquitinases [cytosol] (Rattus norvegicus)

Other forms of this molecule

phospho-Cyld [cytosol]

Cyld [cytosol]

Inferred From

CYLD [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001017380.1, XP_063134160.1, XP_063134163.1, XP_063134156.1, XP_063134155.1, XP_063134162.1, XP_063134157.1, XP_063134154.1, XP_063134158.1, XP_063134164.1, XP_063134161.1

PRO

Q66H62

RGD

1308346