Reactome | Btbd1 [cytosol]

Btbd1 [cytosol]

Stable Identifier

R-RNO-8851650

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

BTBD1, Q5RKI2

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Neddylation (Rattus norvegicus)
    - AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)
      - NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
      - NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
        
        CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
      - CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
        
        CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
        
        RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
        
        NEDD8-CUL3:RBX1:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
    - NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)
      - CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)
      - NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
        
        CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
        
        BTB proteins [cytosol] (Rattus norvegicus)
        
        Btbd1 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q5RKI2

Gene Names

Btbd1

Reference Genes

BioGPS Gene:293060 Btbd1

ENSEMBL:ENSRNOG00000019529

ENSEMBL:ENSRNOG00000019529.6 Btbd1

KEGG Gene (Rattus norvegicus):293060 Btbd1

Monarch:293060 Btbd1

NCBI Gene:293060 Btbd1

UCSC:Q5RKI2 Btbd1

Reference Transcript

RefSeq:NM_001011932.1 Btbd1

Other Identifiers

10723323

1372720_at

1376333_at

17634559

293060

5665394

5915414

6081143

6239838

6247196

6517670

6549250

6557803

6601457

6688936

6712100

A_44_P193704

A_44_P250488

GE15861

GO:0000932

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0032991

GO:0036464

GO:0042802

GO:0043226

GO:0097602

ILMN_1376965

PH_rn_0007374

rc_AA848449_at

rc_AI146047_at

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)

as a member of

BTB proteins [cytosol] (Rattus norvegicus)

Inferred From

BTBD1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001011932.1

Ensembl

ENSRNOT00000026595, ENSRNOP00000026595, ENSRNOG00000019529

RGD

1310962

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