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HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane]
Stable Identifier
R-RNO-8851921
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by MET (Rattus norvegicus)
MET activates PI3K/AKT signaling (Rattus norvegicus)
Activated MET binds GAB1 and GRB2 (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Rattus norvegicus)
MET phosphorylates GAB1 (Rattus norvegicus)
HGF:p-4Y-MET dimer:GAB1,HGF:p-4Y-MET dimer:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Gab1 [cytosol]
(Rattus norvegicus)
Grb2 [cytosol]
(Rattus norvegicus)
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane]
(Rattus norvegicus)
Participates
as an output of
Activated MET binds GAB1 and GRB2 (Rattus norvegicus)
as a member of
HGF:p-4Y-MET dimer:GAB1,HGF:p-4Y-MET dimer:GRB2:GAB1 [plasma membrane] (Rattus norvegicus)
Inferred From
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane]
(Homo sapiens)
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