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Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane]
Stable Identifier
R-RNO-8866535
Type
Complex
Species
Rattus norvegicus
Compartment
endoplasmic reticulum membrane
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Rattus norvegicus)
ABC-family proteins mediated transport (Rattus norvegicus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Rattus norvegicus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Rattus norvegicus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ERAD complex [endoplasmic reticulum membrane]
(Rattus norvegicus)
Ub-misfolded nascent CFTR [cytosol]
(Rattus norvegicus)
Participates
as an input of
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Rattus norvegicus)
as an output of
RNF5 and RNF185 ubiquitinate misfolded CFTR (Rattus norvegicus)
Inferred From
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane]
(Homo sapiens)
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