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EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane]
Stable Identifier
R-RNO-8867035
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by EGFR (Rattus norvegicus)
EGFR downregulation (Rattus norvegicus)
EGFR phosphorylates EPS15 (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Rattus norvegicus)
PTPN3 dephosphorylates EPS15 (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin [plasma membrane]
(Rattus norvegicus)
EPN1 [plasma membrane]
(Rattus norvegicus)
Eps15l1 [plasma membrane]
(Rattus norvegicus)
p-Eps15:HGS:STAM [cytosol]
(Rattus norvegicus)
PI(4,5)P2 [plasma membrane]
Participates
as an input of
PTPN3 dephosphorylates EPS15 (Rattus norvegicus)
as an output of
EGFR phosphorylates EPS15 (Rattus norvegicus)
Inferred From
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane]
(Homo sapiens)
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