Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
KEAP1:NEDD8-CUL3:RBX1 [cytosol]
Stable Identifier
R-RNO-8932333
Type
Complex
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
KEAP1-NFE2L2 pathway (Rattus norvegicus)
CUL3:RBX1 ubiquitinates KEAP1 (Rattus norvegicus)
SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Rattus norvegicus)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
SESN1,SESN1 bind SQSTM1 and KEAP1 (Rattus norvegicus)
SESN1,2:ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Neddylation (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
NFE2L2 inducers:KEAP1:CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Cul3 [cytosol]
(Rattus norvegicus)
Keap1 [cytosol]
(Rattus norvegicus)
Rbx1 [cytosol]
(Rattus norvegicus)
Participates
as an output of
Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Rattus norvegicus)
as a component of
KEAP1:NEDD8-CUL3:RBX1:NFE2L2 [cytosol] (Rattus norvegicus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
ub-K420 p-S349 SQSTM1 oligomer:KEAP1:NEDD8-CUL3:RBX1 [cytosol] (Rattus norvegicus)
as an input of
p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Rattus norvegicus)
Inferred From
KEAP1:NEDD8-CUL3:RBX1 [cytosol]
(Homo sapiens)
KEAP1:NEDD8-CUL3:RBX1 [cytosol]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text