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phospho-Shc1 [cytosol]
Stable Identifier
R-RNO-8934452
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
p-S139,3Y-SHC1-1, Q5M824
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ERBB2 (Rattus norvegicus)
SHC1 events in ERBB2 signaling (Rattus norvegicus)
Activated PKC phosphorylates SHC1 (Rattus norvegicus)
phospho-Shc1 [cytosol] (Rattus norvegicus)
SHC1 binds PTPN12 (Rattus norvegicus)
p-S139,3Y-SHC1-1,p-S29,3Y-SHC1-2:PTPN12 [cytosol] (Rattus norvegicus)
phospho-Shc1 [cytosol] (Rattus norvegicus)
phospho-Shc1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q5M824 Shc1
Gene Names
Shc1
Chain
chain:1-469
Reference Genes
BioGPS Gene:85385 Shc1
KEGG:rno:85385 Shc1
Monarch:85385 Shc1
NCBI Gene:85385 Shc1
UCSC:Q5M824 Shc1
Reference Transcript
RefSeq:NM_053517.2 Shc1
Participates
as an input of
SHC1 binds PTPN12 (Rattus norvegicus)
as a component of
p-S139,3Y-SHC1-1,p-S29,3Y-SHC1-2:PTPN12 [cytosol] (Rattus norvegicus)
as an output of
Activated PKC phosphorylates SHC1 (Rattus norvegicus)
Other forms of this molecule
p-Y314-Shc1 [cytosol]
Shc1 [cytosol]
Shc1 [plasma membrane]
Shc1 [plasma membrane]
Shc1 [plasma membrane]
phospho-Shc1 [cytosol]
phospho-Shc1 [cytosol]
Shc1 [cytosol]
Shc1 [cytosol]
phospho-Shc1 [cytosol]
phospho-Shc1 [cytosol]
phospho-Shc1 [cytosol]
phospho-Shc1 [cytosol]
phospho-Shc1 [plasma membrane]
phospho-Shc1 [plasma membrane]
phospho-Shc1 [cytosol]
Shc1 [cytosol]
phospho-Shc1 [cytosol]
Inferred From
p-S139,3Y-SHC1-1,p-S29,3Y-SHC1-2 [cytosol]
(Homo sapiens)
p-S139,3Y-SHC1-1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 349 (in Homo sapiens)
Coordinate
349
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 350 (in Homo sapiens)
Coordinate
350
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 427 (in Homo sapiens)
Coordinate
427
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-serine at 139 (in Homo sapiens)
Coordinate
139
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_445969.2
PRO
Q5M824
RGD
620446
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:B5DFH1 B5DFH1
0.463
2
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