Runx2 binds p-Y-Yap1

Stable Identifier
R-RNO-8937926
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Runx2 binds p-Y-Yap1
In rat osteosarcoma cells, Runx2, presumably associated with Cbfb, forms a complex with Yap1, phosphorylated on an unknown tyrosine residue by Src and/or Yes1. The interaction involves the PY motif of Runx2 (Zaidi et al. 2004).
Literature References
PubMed ID Title Journal Year
14765127 Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

van Wijnen, AJ, Ito, Y, Medina, R, Lian, JB, Stein, JL, Stein, GS, Sullivan, AJ, Zaidi, SK

EMBO J. 2004
Participants
Input
Output
Orthologous Events
RUNX2 binds tyrosine phosphorylated YAP1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2016-09-07)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2016-09-07)
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