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About
What is Reactome ?
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Team
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License Agreement
Privacy Notice
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Digital Preservation
Contact us
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CALM1 [cytosol]
Stable Identifier
R-RNO-9016707
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
P0DP31
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to mechanical stimuli (Rattus norvegicus)
Response of endothelial cells to shear stress (Rattus norvegicus)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Rattus norvegicus)
TRPV4 tetramer binds CALM1:Ca2+ (calmodulin:Ca2+) (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
TRPV4 tetramer:CALM1:Ca2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Hemostasis (Rattus norvegicus)
Platelet activation, signaling and aggregation (Rattus norvegicus)
Response to elevated platelet cytosolic Ca2+ (Rattus norvegicus)
Platelet degranulation (Rattus norvegicus)
Release of platelet cytosolic components (Rattus norvegicus)
Platelet releasate cytosolic proteins [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Platelet homeostasis (Rattus norvegicus)
Platelet calcium homeostasis (Rattus norvegicus)
Reduction of cytosolic Ca++ levels (Rattus norvegicus)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Signaling by the B Cell Receptor (BCR) (Rattus norvegicus)
Downstream signaling events of B Cell Receptor (BCR) (Rattus norvegicus)
Calcineurin activates NFAT (Rattus norvegicus)
Calcineurin binds NFATC1,2,3 (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Calcineurin:p-NFATC1,2,3 [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
C-type lectin receptors (CLRs) (Rattus norvegicus)
CLEC7A (Dectin-1) signaling (Rattus norvegicus)
CLEC7A (Dectin-1) induces NFAT activation (Rattus norvegicus)
Activation of Calcineurin (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Calcineurin binds and dephosphorylates NFAT (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
NFAT:CaN:CaM [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Translocation of CaN:CaM:NFAT to nucleus (Rattus norvegicus)
NFAT:CaN:CaM [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
FCERI mediated Ca+2 mobilization (Rattus norvegicus)
Activation of Calcineurin (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Calcineurin binds and dephosphorylates NFAT (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
NFAT:CaN:CaM [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Translocation of CaN:CaM:NFAT to nucleus (Rattus norvegicus)
NFAT:CaN:CaM [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Metabolism (Rattus norvegicus)
Inositol phosphate metabolism (Rattus norvegicus)
Synthesis of IP3 and IP4 in the cytosol (Rattus norvegicus)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Rattus norvegicus)
ITPKA/B/C [cytosol] (Rattus norvegicus)
ITPKA:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
ITPKB:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
ITPKC:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Metabolism of carbohydrates (Rattus norvegicus)
Glycogen metabolism (Rattus norvegicus)
Glycogen breakdown (glycogenolysis) (Rattus norvegicus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Rattus norvegicus)
phosphorylase kinase complex (PHKL) [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Rattus norvegicus)
phosphorylase kinase complex (PHKM) [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Metabolism of nitric oxide: NOS3 activation and regulation (Rattus norvegicus)
eNOS activation (Rattus norvegicus)
AKT1 phosphorylates eNOS (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
BH2 binding can lead to eNOS uncoupling (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
HSP90 binds eNOS:Caveolin-1:CaM complex (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Uncoupled eNOS favours the formation of superoxide (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
eNOS:Caveolin-1 complex binds to CaM (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of cofactors (Rattus norvegicus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Rattus norvegicus)
BH2 binding can lead to eNOS uncoupling (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Protein methylation (Rattus norvegicus)
KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Muscle contraction (Rattus norvegicus)
Cardiac conduction (Rattus norvegicus)
Ion homeostasis (Rattus norvegicus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Rattus norvegicus)
CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Smooth Muscle Contraction (Rattus norvegicus)
MYLK (MLCK) Active Calmodulin Binding (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
MYLK:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Phosphorylation of Smooth Muscle Myosin Light Chains (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
MYLK:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
Activation of NMDA receptors and postsynaptic events (Rattus norvegicus)
Post NMDA receptor activation events (Rattus norvegicus)
Activation of RAC1 downstream of NMDARs (Rattus norvegicus)
CAMK1 binds calmodulin (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
CAMK1:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
CaMKK autophosphorylates in the cytosol (Rattus norvegicus)
CaMKK:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
p-CaMKK:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Unblocking of NMDA receptors, glutamate binding and activation (Rattus norvegicus)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Rattus norvegicus)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Rattus norvegicus)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Activation of kainate receptors upon glutamate binding (Rattus norvegicus)
Ionotropic activity of kainate receptors (Rattus norvegicus)
Activation of Ca-permeable Kainate Receptor (Rattus norvegicus)
Activation of Ca-permeable Kainate receptors (Rattus norvegicus)
Kainate receptor-glutamate complex [plasma membrane] (Rattus norvegicus)
Kainate Receptors [plasma membrane] (Rattus norvegicus)
GRIK 2 homomer [plasma membrane] (Rattus norvegicus)
GRIK2 interacting proteins [plasma membrane] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
kainate receptor binds glutamate (Rattus norvegicus)
Kainate Receptors [plasma membrane] (Rattus norvegicus)
GRIK 2 homomer [plasma membrane] (Rattus norvegicus)
GRIK2 interacting proteins [plasma membrane] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Kainate receptor-glutamate complex [plasma membrane] (Rattus norvegicus)
Kainate Receptors [plasma membrane] (Rattus norvegicus)
GRIK 2 homomer [plasma membrane] (Rattus norvegicus)
GRIK2 interacting proteins [plasma membrane] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Sensory Perception (Rattus norvegicus)
Visual phototransduction (Rattus norvegicus)
The phototransduction cascade (Rattus norvegicus)
Inactivation, recovery and regulation of the phototransduction cascade (Rattus norvegicus)
CALM1:Ca2+ binds CNG channel (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
CALM1:Ca2+:CNG channel [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
DAG and IP3 signaling (Rattus norvegicus)
CaM pathway (Rattus norvegicus)
Calmodulin induced events (Rattus norvegicus)
Cam-PDE 1 activation (Rattus norvegicus)
Calmodulin activates Cam-PDE 1 (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
GRK2 binds CALM1:4Ca2+ (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
GRK2:CALM1:4xCa2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
PKA-mediated phosphorylation of CREB (Rattus norvegicus)
PKA activation (Rattus norvegicus)
Adenylate cyclase produces cAMP (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
RAF activation (Rattus norvegicus)
Phosphorylation of RAF (Rattus norvegicus)
RAF activating kinases [plasma membrane] (Rattus norvegicus)
p-T286-CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
RAS GEFs [plasma membrane] (Rattus norvegicus)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
RAS processing (Rattus norvegicus)
ARL2:GTP bind PDE6D on KRAS4B (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D:ARL2:GTP [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Calmodulin dissociates KRAS4B from the plasma membrane (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
KRAS4B recycles to the plasma membrane (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D:ARL2:GTP [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+:PDE6D [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B binds calmodulin (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Opioid Signalling (Rattus norvegicus)
G-protein mediated events (Rattus norvegicus)
PLC beta mediated events (Rattus norvegicus)
Ca-dependent events (Rattus norvegicus)
CaM pathway (Rattus norvegicus)
Calmodulin induced events (Rattus norvegicus)
Cam-PDE 1 activation (Rattus norvegicus)
Calmodulin activates Cam-PDE 1 (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
GRK2 binds CALM1:4Ca2+ (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
GRK2:CALM1:4xCa2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
PKA-mediated phosphorylation of CREB (Rattus norvegicus)
PKA activation (Rattus norvegicus)
Adenylate cyclase produces cAMP (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Extra-nuclear estrogen signaling (Rattus norvegicus)
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
VEGFR2 mediated vascular permeability (Rattus norvegicus)
AKT1 phosphorylates eNOS (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
HSP90 binds eNOS:Caveolin-1:CaM complex (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
eNOS:Caveolin-1 complex binds to CaM (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases activate PAKs (Rattus norvegicus)
MYLK (MLCK) Active Calmodulin Binding (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
MYLK:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Signaling by WNT (Rattus norvegicus)
Beta-catenin independent WNT signaling (Rattus norvegicus)
Ca2+ pathway (Rattus norvegicus)
Activation of Calcineurin (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Active calmodulin binds CAMK2 (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
CAMK2:CaM [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
S-Farn-Me KRAS4B:CALM1:4xCa2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Autophosphorylation and activation of CAMK2 (Rattus norvegicus)
CAMK2:CaM [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
p-T286 CAMK2:CaM [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
NFATC1:CaN:CaM [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Dissociation of CaM and CAMK2 autophosphorylation (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
p-T286 CAMK2:CaM [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Translocation of NFATC1:CaN:CaM to nucleus (Rattus norvegicus)
NFATC1:CaN:CaM [cytosol] (Rattus norvegicus)
Calcineurin:Calmodulin (CaN:CaM) [cytosol] (Rattus norvegicus)
PPP3CA,B:Calmodulin [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Transport of small molecules (Rattus norvegicus)
Ion channel transport (Rattus norvegicus)
Ion transport by P-type ATPases (Rattus norvegicus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Rattus norvegicus)
CAMK2 heteromer:CALM:4xCa2+ [plasma membrane] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
Stimuli-sensing channels (Rattus norvegicus)
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Rattus norvegicus)
Sodium/Calcium exchangers (Rattus norvegicus)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Rattus norvegicus)
CALM1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P0DP31
Reference Genes
BioGPS Gene:24242
BioGPS Gene:24244
BioGPS Gene:50663
ENSEMBL:ENSRNOG00000004060
ENSEMBL:ENSRNOG00000004060.8
ENSEMBL:ENSRNOG00000016770
ENSEMBL:ENSRNOG00000067086
ENSEMBL:ENSRNOG00055015152
ENSEMBL:ENSRNOG00055031474
ENSEMBL:ENSRNOG00060022413
ENSEMBL:ENSRNOG00065014668
ENSEMBL:ENSRNOG00065032582
KEGG Gene (Rattus norvegicus):24242
KEGG Gene (Rattus norvegicus):24244
KEGG Gene (Rattus norvegicus):50663
Monarch:24242
Monarch:24244
Monarch:50663
NCBI Gene:24242
NCBI Gene:24244
NCBI Gene:50663
Reference Transcript
RefSeq:NM_012518.3
RefSeq:NM_031969.2
RefSeq:NM_017326.3
Other Identifiers
10886378
1369936_at
1369937_at
1387772_at
17817885
24242
5707715
5998008
6072595
6208193
6278158
6281298
6324468
6345774
6358736
6454567
6467729
6497821
6623834
6669162
6718682
A_44_P191784
A_44_P374988
A_64_P015022
E02315cds_f_at
GO:0005509
ILMN_1376284
PH_rn_0012310
X13933_s_at
rc_AA849525_s_at
rc_AI102076_at
rc_AI171814_at
rc_AI180372_f_at
Participates
as a member of
Platelet releasate cytosolic proteins [cytosol] (Rattus norvegicus)
as an input of
KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Rattus norvegicus)
as a component of
GRIK2 interacting proteins [plasma membrane] (Rattus norvegicus)
phosphorylase kinase complex (PHKM) [cytosol] (Rattus norvegicus)
phosphorylase kinase complex (PHKL) [cytosol] (Rattus norvegicus)
ITPKB:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
ITPKC:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
ITPKA:Ca2+:CALM1 [cytosol] (Rattus norvegicus)
CALM1:4xCa2+ [cytosol] (Rattus norvegicus)
This entity regulates
Negatively
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol
(Rattus norvegicus)
SLC8A1,2,3 exchange 3Na+ for Ca2+
(Rattus norvegicus)
Other forms of this molecule
CALM1 [extracellular region]
Me3K116-CALM1 [cytosol]
CALM1 [plasma membrane]
CALM1 [nucleoplasm]
Inferred From
CALM1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_036650.1
,
NP_114175.1
,
NP_059022.1
Ensembl
ENSRNOP00000063822
,
ENSRNOG00000004060
,
ENSRNOT00000064679
PRO
P0DP31
RGD
2259
,
2258
,
2257
PDB
3EK8
,
3EK4
,
3EKH
,
3WLD
,
3SG2
,
3SG6
,
3EVU
,
3SG4
,
3EKJ
,
3WLC
,
3EK7
,
3SG3
,
4I2Y
,
3SG7
,
1UP5
,
3EVV
,
3SG5
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