(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine

Stable Identifier
R-RNO-909775
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine
Mitochondrial Agxt2 tetramer catalyzes the reaction of (R)-3-aminoisobutyric acid and pyruvate to form 2-methyl-3-oxopropanoate and alanine (Lee et al. 1995; Tamaki et al. 1990).
Literature References
PubMed ID Title Journal Year
2158891 Purification, characterization and inhibition of D-3-aminoisobutyrate aminotransferase from the rat liver

Mizota, C, Kaneko, M, Kikugawa, M, Fujimoto, S, Tamaki, N

Eur J Biochem 1990
7592550 Molecular cloning and sequencing of a cDNA encoding alanine-glyoxylate aminotransferase 2 from rat kidney

Lee, IS, Kido, R, Tsuji, M, Ideguchi, T, Okuno, E, Hase, T, Ooshima, A, Muragaki, Y

J Biochem 1995
Participants
Catalyst Activity

(R)-3-amino-2-methylpropionate-pyruvate transaminase activity of Agxt2 tetramer [mitochondrial matrix]

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