Reactome | Vamp2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]

Vamp2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]

Stable Identifier

R-RNO-917738

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane

Synonyms

VAMP2, P63045

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P63045

Gene Names

Vamp2

Reference Genes

BioGPS Gene:24803 Vamp2

ENSEMBL:ENSRNOG00000006989

ENSEMBL:ENSRNOG00000006989.8 Vamp2

ENSEMBL:ENSRNOG00055032376

ENSEMBL:ENSRNOG00060030134

ENSEMBL:ENSRNOG00065025916

KEGG Gene (Rattus norvegicus):24803 Vamp2

Monarch:24803 Vamp2

NCBI Gene:24803 Vamp2

UCSC:P63045 Vamp2

Reference Transcript

RefSeq:NM_012663.2 Vamp2

Other Identifiers

10734875

1369974_at

17647366

24803

5803718

5939350

6052414

6219619

6350008

6367358

6503118

6533731

6665395

A_44_P447539

GE1167038

GO:0016020

GO:0016192

ILMN_1360798

M24105_at

PH_rn_0012044

rc_AA944789_f_at

rc_AA998361_f_at

rc_AI101103_s_at

Participates

as a component of

GABA Loaded synaptic vesicle [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (Rattus norvegicus)

Other forms of this molecule

Vamp2 [clathrin-coated endocytic vesicle membrane]

Vamp2 [Golgi membrane]

Vamp2 [lysosomal membrane]

Vamp2 [cytoplasmic vesicle membrane]

Vamp2 [clathrin-sculpted monoamine transport vesicle membrane]

Vamp2 [plasma membrane]

Vamp2 [clathrin-sculpted glutamate transport vesicle membrane]

Vamp2 [secretory granule membrane]

Vamp2 [cytosol]

Inferred From

VAMP2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_036795.1

Ensembl

ENSRNOG00000006989, ENSRNOP00000054114, ENSRNOT00000057295

PRO

P63045

RGD

3949

PDB

6MDM, 3IPD, 3J98, 6WVW, 6MTI, 5W5D, 6A30, 3J99, 7UDB, 2N1T, 1KIL, 5CCG, 6IP1, 5CCH, 1N7S, 3J97, 3J96, 5CCI, 2KOG, 5W5C, 1SFC, 3HD7, 6MDN

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P60881	3	Snap25 [specific granule membrane] (R-RNO-6806154) Snap25 [tertiary granule membrane] (R-RNO-6806142) Snap25 [plasma membrane] (R-RNO-2029017)	0.949	15
UniProt:P32851 Stx1a	2	Stx1a [cytosol] (R-RNO-9609866) Stx1a [plasma membrane] (R-RNO-6794247)	0.752	9
UniProt:Q08850	4	phospho-Stx4 [cytosol] (R-RNO-114681) Stx4 [cytosol] (R-RNO-114505) Stx4 [plasma membrane] (R-RNO-181519) Stx4 [phagocytic vesicle membrane] (R-RNO-2029044)	0.697	8
UniProt:P60881-2 SNAP25			0.667	4
UniProt:P21707	6	SYT1 [clathrin-sculpted monoamine transport vesicle membrane] (R-RNO-372508) SYT1 [plasma membrane] (R-RNO-168786) SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-RNO-917741) SYT1 [clathrin-sculpted glutamate transport vesicle membrane] (R-RNO-372514) SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane] (R-RNO-210536) SYT1 [clathrin-coated endocytic vesicle membrane] (R-RNO-8869113)	0.609	7
UniProt:P07825 SYPH			0.609	5
UniProt:P63041	1	Cplx1 [cytosol] (R-RNO-210385)	0.564	2
UniProt:O70377	4	Snap23 [specific granule membrane] (R-RNO-6806157) Snap23 [plasma membrane] (R-RNO-376345) Snap23 [tertiary granule membrane] (R-RNO-6806141) phospho-Snap23 [phagocytic vesicle membrane] (R-RNO-8863923)	0.564	4
UniProt:O35394 PRAF1			0.527	2
UniProt:P63045	10	Vamp2 [clathrin-coated endocytic vesicle membrane] (R-RNO-8869129) Vamp2 [Golgi membrane] (R-RNO-375425) Vamp2 [lysosomal membrane] (R-RNO-432703) Vamp2 [cytoplasmic vesicle membrane] (R-RNO-1449630) Vamp2 [clathrin-sculpted monoamine transport vesicle membrane] (R-RNO-379363) Vamp2 [plasma membrane] (R-RNO-210516) Vamp2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-RNO-917738) Vamp2 [clathrin-sculpted glutamate transport vesicle membrane] (R-RNO-210365) Vamp2 [secretory granule membrane] (R-RNO-376363) Vamp2 [cytosol] (R-RNO-9609882)	0.524	2
UniProt:P18708 NSF			0.488	2

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