Reactome | Uba52 [cytosol]

Uba52 [cytosol]

Stable Identifier

R-RNO-939202

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

Ub-48-RPS27A(1-76), P62986

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Death Receptor Signaling (Rattus norvegicus)
  - TNF signaling (Rattus norvegicus)
    - Regulation of TNFR1 signaling (Rattus norvegicus)
      - TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Rattus norvegicus)
        
        K48polyUb [cytosol] (Rattus norvegicus)
        
        K48-Ub [cytosol] (Rattus norvegicus)
        
        Uba52 [cytosol] (Rattus norvegicus)
        
        K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Rattus norvegicus)
        
        K48polyUb [cytosol] (Rattus norvegicus)
        
        K48-Ub [cytosol] (Rattus norvegicus)
        
        Uba52 [cytosol] (Rattus norvegicus)
- MAPK family signaling cascades (Rattus norvegicus)
  - MAPK1/MAPK3 signaling (Rattus norvegicus)
    - RAF/MAP kinase cascade (Rattus norvegicus)
      - RAS processing (Rattus norvegicus)
        
        USP17L2 deubiquitinates RCE1 (Rattus norvegicus)
        
        PolyUb [cytosol] (Rattus norvegicus)
        
        K48polyUb [cytosol] (Rattus norvegicus)
        
        K48-Ub [cytosol] (Rattus norvegicus)
        
        Uba52 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P62986

Gene Names

Uba52

Reference Genes

BioGPS Gene:64156 UBIQ

ENSEMBL:ENSRNOG00000019971

ENSEMBL:ENSRNOG00000019974

ENSEMBL:ENSRNOG00000090524

KEGG:rno:64156 UBIQ

Monarch:64156 UBIQ

NCBI Gene:64156 UBIQ

UCSC:P62986 Uba52

Reference Transcript

Other Identifiers

10787544

1398754_at

17707146

6078928

6266531

64156

6492767

6502853

6638007

6685017

GO:0002181

GO:0003735

GO:0005198

GO:0005515

GO:0005634

GO:0005737

GO:0005840

GO:0006412

GO:0015934

GO:0016567

GO:0017085

GO:0019941

GO:0022625

GO:0022626

GO:0031386

GO:0031625

GO:0045202

GO:0098556

GO:1990904

ILMN_1351207

PH_rn_0011321

rc_AA818888_at

Participates

as a member of

K48-Ub [cytosol] (Rattus norvegicus)

Other forms of this molecule

Uba52 [cytosol]

Uba52 [nucleoplasm]

Uba52 [cytosol]

Uba52 [nucleoplasm]

Uba52 [endoplasmic reticulum membrane]

Uba52 [cytosol]

Uba52 [mitochondrial outer membrane]

Uba52 [endosome membrane]

phospho-Uba52 [cytosol]

Uba52 [cytosol]

phospho-Uba52 [nucleoplasm]

Uba52 [cytosol]

Uba52 [mitochondrial outer membrane]

Uba52 [nucleoplasm]

Uba52 [endocytic vesicle membrane]

Inferred From

Ub-48-RPS27A(1-76) [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine at 48 (in Homo sapiens)

Coordinate

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

XP_063131755.1, NP_113875.1, XP_006252997.1, XP_008769368.1

ENSEMBL

ENSRNOP00000027073, ENSRNOT00000027073, ENSRNOG00000090524

PRO

P62986

GlyGen

P62986

RGD

68344