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About
What is Reactome ?
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Release Calendar
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License Agreement
Privacy Notice
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Digital Preservation
Contact us
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Table of Contents
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Ube2s [cytosol]
Stable Identifier
R-RNO-947622
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
UBE2S, B5DFI8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle Checkpoints (Rattus norvegicus)
Mitotic Spindle Checkpoint (Rattus norvegicus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Rattus norvegicus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Rattus norvegicus)
Binding of the MCC complex to the APC/C complex (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Metaphase and Anaphase (Rattus norvegicus)
Mitotic Anaphase (Rattus norvegicus)
Separation of Sister Chromatids (Rattus norvegicus)
Association of Securin with Cdc20:APC/C complex (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated Securin (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Regulation of mitotic cell cycle (Rattus norvegicus)
APC/C-mediated degradation of cell cycle proteins (Rattus norvegicus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Rattus norvegicus)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Rattus norvegicus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated cell cycle proteins (Rattus norvegicus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Rattus norvegicus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Rattus norvegicus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Rattus norvegicus)
APC/C:Cdc20 mediated degradation of Cyclin B (Rattus norvegicus)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated Cyclin B (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Rattus norvegicus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Rattus norvegicus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
APC/C:Cdc20 mediated degradation of Securin (Rattus norvegicus)
Association of Securin with Cdc20:APC/C complex (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated Securin (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Rattus norvegicus)
CDC20:p-APC/C:PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Rattus norvegicus)
APC-Cdc20 mediated degradation of Nek2A (Rattus norvegicus)
Association of Nek2A with MCC:APC/C (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Degradation of multiubiquitinated Nek2A (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Multiubiquitinated Nek2A [cytosol] (Rattus norvegicus)
Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Multiubiquitination of Nek2A (Rattus norvegicus)
Multiubiquitinated Nek2A [cytosol] (Rattus norvegicus)
Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Nek2A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Rattus norvegicus)
Association of Cyclin A with the APC/C (Rattus norvegicus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Degradation multiubiquitinated Cyclin A (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Rattus norvegicus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Rattus norvegicus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Rattus norvegicus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Rattus norvegicus)
Association of Cdh1 with the APC/C (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Dissociation of Cdc20 from APC/C complex (Rattus norvegicus)
CDC20:p-APC/C [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Regulation of APC/C activators between G1/S and early anaphase (Rattus norvegicus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Rattus norvegicus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Rattus norvegicus)
Binding of the MCC complex to the APC/C complex (Rattus norvegicus)
MCC:APC/C complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
S Phase (Rattus norvegicus)
Synthesis of DNA (Rattus norvegicus)
Switching of origins to a post-replicative state (Rattus norvegicus)
CDK-mediated phosphorylation and removal of Cdc6 (Rattus norvegicus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
DNA Replication (Rattus norvegicus)
Synthesis of DNA (Rattus norvegicus)
Switching of origins to a post-replicative state (Rattus norvegicus)
CDK-mediated phosphorylation and removal of Cdc6 (Rattus norvegicus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Rattus norvegicus)
phospho-APC/C:Cdh1 complex [cytosol] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
Antigen processing: Ubiquitination & Proteasome degradation (Rattus norvegicus)
Interaction of E3 with substrate and E2-Ub complex (Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Rattus norvegicus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Rattus norvegicus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Polyubiquitination of substrate (Rattus norvegicus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Rattus norvegicus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Rattus norvegicus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Transfer of ubiquitin from E1 to E2 (Rattus norvegicus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Ubiquitin:E2 conjugating enzymes [cytosol] (Rattus norvegicus)
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Protein ubiquitination (Rattus norvegicus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Rattus norvegicus)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Rattus norvegicus)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Rattus norvegicus)
E2 ubiquitin conjugating enzyme (UBA6 substrate) [cytosol] (Rattus norvegicus)
Ube2s [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:B5DFI8
Gene Names
Ube2s
Reference Genes
BioGPS Gene:292588 Ube2s
ENSEMBL:ENSRNOG00000016930
ENSEMBL:ENSRNOG00000016930.6 Ube2s
ENSEMBL:ENSRNOG00055014224
ENSEMBL:ENSRNOG00060026151
ENSEMBL:ENSRNOG00065032252
KEGG Gene (Rattus norvegicus):292588 Ube2s
Monarch:292588 Ube2s
NCBI Gene:292588 Ube2s
UCSC:B5DFI8 Ube2s
Reference Transcript
RefSeq:NM_001106224.2 Ube2s
Other Identifiers
10703947
1371365_at
1397566_at
17613043
292588
5630862
5827625
5876012
5978240
6058106
6125890
6298693
6303860
6336247
6375164
A_42_P505972
A_44_P397736
A_64_P065882
GE1206861
GO:0000278
GO:0003824
GO:0004842
GO:0005634
GO:0005680
GO:0010458
GO:0010994
GO:0010997
GO:0016740
GO:0030163
GO:0031145
GO:0035519
GO:0036211
GO:0043226
GO:0044314
GO:0061631
GO:0065003
GO:0070534
GO:0070979
GO:0085020
GO:0140014
GO:0140096
ILMN_1374643
rc_AI169264_at
Participates
as a member of
E2 ubiquitin conjugating enzyme (UBA6 substrate) [cytosol] (Rattus norvegicus)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Rattus norvegicus)
as a candidate of
E2 Ubiquitin-conjugating enzyme [cytosol] (Rattus norvegicus)
as a component of
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Rattus norvegicus)
Other forms of this molecule
Ube2s [cytosol]
Ube2s [nucleoplasm]
Ube2s [nucleoplasm]
Inferred From
UBE2S [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001099694.1
Ensembl
ENSRNOG00000016930
,
ENSRNOP00000022977
,
ENSRNOT00000022977
PRO
B5DFI8
RGD
1564746
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