Reactome | Mchr1 [plasma membrane]

Mchr1 [plasma membrane]

Stable Identifier

R-RNO-947682

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

MCHR1, P97639

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Rattus norvegicus)
        
        Mchr1 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Rattus norvegicus)
        
        Mchr1 [plasma membrane] (Rattus norvegicus)
    - G alpha (q) signalling events (Rattus norvegicus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Rattus norvegicus)
        
        Mchr1 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Rattus norvegicus)
        
        Mchr1 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Melanin-concentrating hormone receptors bind MCH (Rattus norvegicus)
        
        MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Rattus norvegicus)
        
        Mchr1 [plasma membrane] (Rattus norvegicus)
        
        Mchr1 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P97639

Gene Names

Mchr1

Reference Genes

BioGPS Gene:83567 Mchr1

ENSEMBL:ENSRNOG00000018895

ENSEMBL:ENSRNOG00055032055

ENSEMBL:ENSRNOG00060028081

ENSEMBL:ENSRNOG00065029882

KEGG:rno:83567 Mchr1

Monarch:83567 Mchr1

NCBI Gene:83567 Mchr1

UCSC:P97639 Mchr1

Reference Transcript

RefSeq:NM_031758.1 Mchr1

Other Identifiers

10897897

1369537_at

17830875

5665810

6531117

6550624

83567

AF008650_at

A_44_P290552

GE21300

GO:0004930

GO:0005102

GO:0005886

GO:0005929

GO:0007186

GO:0007218

GO:0016020

GO:0023052

GO:0030273

GO:0043005

GO:0043226

GO:0060089

GO:0060170

GO:0097730

ILMN_1360340

PH_rn_0015113

U77953cds_s_at

Participates

as a candidate of

BBSome ciliary cargo [plasma membrane] (Rattus norvegicus)

as an input of

Melanin-concentrating hormone receptors bind MCH (Rattus norvegicus)

as a component of

MCHR1,MCHR2:PMCH(147-165) [plasma membrane] (Rattus norvegicus)

Other forms of this molecule

Mchr1 [ciliary membrane]

Inferred From

MCHR1,MCHR2 [plasma membrane] (Homo sapiens)

MCHR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_113946.1

ZINC - Investigational

MCHR1_RAT

ENSEMBL

ENSRNOT00000025564, ENSRNOP00000025564

ZINC - Substances

MCHR1_RAT

ZINC target

P97639

PRO

P97639

GlyGen

P97639

RGD

619841

ZINC - Predictions - Purchasable

MCHR1_RAT

HMDB Protein

HMDBP13927

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96E35 ZMY19			0.557	3