Reactome | Gsdmd [cytosol]

Gsdmd [cytosol]

Stable Identifier

R-RNO-9647641

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

GSDMD(1-275), A0A096MJ11

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Cytokine Signaling in Immune system (Rattus norvegicus)
  - Signaling by Interleukins (Rattus norvegicus)
    - Interleukin-1 family signaling (Rattus norvegicus)
      - Interleukin-1 processing (Rattus norvegicus)
        
        Interleukin-1 family are secreted (Rattus norvegicus)
        
        GSDMD pore complex [plasma membrane] (Rattus norvegicus)
        
        GSDMD oligomer:PIPs [plasma membrane] (Rattus norvegicus)
        
        Gsdmd [cytosol] (Rattus norvegicus)
- Innate Immune System (Rattus norvegicus)
  - Toll-like Receptor Cascades (Rattus norvegicus)
    - Regulation of TLR by endogenous ligand (Rattus norvegicus)
      - HMGB1 release from cells (Rattus norvegicus)
        
        GSDMD pore complex [plasma membrane] (Rattus norvegicus)
        
        GSDMD oligomer:PIPs [plasma membrane] (Rattus norvegicus)
        
        Gsdmd [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:A0A096MJ11

Gene Names

Gsdmd

Reference Genes

BioGPS Gene:315084 Gsdmd

ENSEMBL:ENSRNOG00000007728

Monarch:315084 Gsdmd

NCBI Gene:315084 Gsdmd

UCSC:A0A096MJ11 Gsdmd

Reference Transcript

Other Identifiers

10897096

1385001_at

17829986

315084

5645717

5666782

5800586

5814642

5842558

5847918

5888694

5936927

5951713

6041652

6165488

6229785

6234713

6389438

6570802

6572221

6699560

6712542

A_44_P199469

GE1129954

GO:0001778

GO:0001786

GO:0005546

GO:0005615

GO:0005654

GO:0005829

GO:0005886

GO:0006629

GO:0006954

GO:0009306

GO:0012501

GO:0016020

GO:0022829

GO:0031966

GO:0032731

GO:0035655

GO:0042742

GO:0044546

GO:0046513

GO:0046931

GO:0050729

GO:0050829

GO:0050830

GO:0051260

GO:0051604

GO:0055085

GO:0061024

GO:0065003

GO:0070269

GO:0070273

GO:0070300

GO:0070498

GO:0072559

GO:0098542

GO:0141201

GO:1901612

ILMN_1364932

PH_rn_0008507

Participates

as an input of

as a component of

as an output of

CASP1 cleaves GSDMD (Rattus norvegicus)

Other forms of this molecule

Gsdmd [ficolin-1-rich granule lumen]

Gsdmd [specific granule lumen]

Gsdmd [extracellular region]

Gsdmd [tertiary granule lumen]

Gsdmd [cytosol]

Inferred From

GSDMD(1-275) [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006241871.1, NP_001387922.1, NP_001387923.1

ENSEMBL

ENSRNOT00000075917, ENSRNOG00000007728, ENSRNOP00000067951

RGD

1307261