Reactome | KCNJ10 [plasma membrane]

KCNJ10 [plasma membrane]

Stable Identifier

R-RNO-975290

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

P49655

Locations in the PathwayBrowser

Expand all

Neuronal System (Rattus norvegicus)

- Potassium Channels (Rattus norvegicus)
  - Inwardly rectifying K+ channels (Rattus norvegicus)
    - G protein gated Potassium channels (Rattus norvegicus)
      - Activation of G protein gated Potassium channels (Rattus norvegicus)
        
        Activation of GIRK/Kir3 Channels (Rattus norvegicus)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Rattus norvegicus)
        
        Kir heterotetramers [plasma membrane] (Rattus norvegicus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Rattus norvegicus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir heterotetramers [plasma membrane] (Rattus norvegicus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Rattus norvegicus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Rattus norvegicus)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Rattus norvegicus)
        
        Kir heterotetramers [plasma membrane] (Rattus norvegicus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Rattus norvegicus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir heterotetramers [plasma membrane] (Rattus norvegicus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Rattus norvegicus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
    - Potassium transport channels (Rattus norvegicus)
      - Activation of Potassium transport channels (Rattus norvegicus)
        
        Potassium transport channels (Kir 1.1 and Kir 4.1/5.1) [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
- Transmission across Chemical Synapses (Rattus norvegicus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
    - GABA receptor activation (Rattus norvegicus)
      - GABA B receptor activation (Rattus norvegicus)
        
        Activation of GABAB receptors (Rattus norvegicus)
        
        Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (Rattus norvegicus)
        
        Activation of GIRK/Kir3 Channels (Rattus norvegicus)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Rattus norvegicus)
        
        Kir heterotetramers [plasma membrane] (Rattus norvegicus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Rattus norvegicus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir heterotetramers [plasma membrane] (Rattus norvegicus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Rattus norvegicus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Binding of Gbeta/gamma to GIRK/Kir3 channels (Rattus norvegicus)
        
        GABA B receptor G-protein beta-gamma and Kir3 channel complex [plasma membrane] (Rattus norvegicus)
        
        Kir heterotetramers [plasma membrane] (Rattus norvegicus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Rattus norvegicus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir heterotetramers [plasma membrane] (Rattus norvegicus)
        
        Kir2.1:Kirx.x heterotetramer [plasma membrane] (Rattus norvegicus)
        
        Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)
        
        Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)
        
        KCNJ10 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P49655

Reference Genes

BioGPS Gene:29718

ENSEMBL:ENSRNOG00000007705

ENSEMBL:ENSRNOG00000068444

ENSEMBL:ENSRNOG00000068444.1

ENSEMBL:ENSRNOG00055021910

ENSEMBL:ENSRNOG00060022823

ENSEMBL:ENSRNOG00065026536

KEGG Gene (Rattus norvegicus):29718

Monarch:29718

NCBI Gene:29718

UCSC:P49655

Reference Transcript

Other Identifiers

10765740

1383086_at

1387467_at

17682108

29718

5627034

5725102

6353597

6479796

6560718

6618476

6626386

6730187

A_43_P12609

A_64_P101968

GE1126177

GE1306628

GE16657

GO:0005215

GO:0005242

GO:0006813

GO:0016020

ILMN_1357099

U27558_at

X83585cds_s_at

rc_AI102244_at

Participates

as a component of

Kir4.1:Kir5.1 heterotetramer [plasma membrane] (Rattus norvegicus)

as a member of

Kirx.x that interacts with Kir2.1 [plasma membrane] (Rattus norvegicus)

Inferred From

KCNJ10 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_017454263.1, NP_113790.2, XP_008767959.1

Ensembl

ENSRNOP00000086322, ENSRNOT00000119639, ENSRNOG00000068444

PRO

P49655

RGD

61822

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O54824	4	Il16 [extracellular region] (R-MMU-447098) Il16 [cytosol] (R-MMU-449094) Il16 [cytosol] (R-MMU-449075) Il16 [cytosol] (R-MMU-449071)	0.527	2

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