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Klhl21 [cytosol]
Stable Identifier
R-RNO-976026
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
KLHL21, D4A2K4
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
Antigen processing: Ubiquitination & Proteasome degradation (Rattus norvegicus)
Interaction of E3 with substrate and E2-Ub complex (Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
Polyubiquitination of substrate (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
E3:K48-polyubiquitinated substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
E3:Ub:substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
Release of E3 from polyubiquitinated substrate (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
E3:K48-polyubiquitinated substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)
Ag-substrate:E3:E2:Ub [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
E3:Ub:substrate [cytosol] (Rattus norvegicus)
E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Neddylation (Rattus norvegicus)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-CUL3:RBX1:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Rattus norvegicus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
NEDD8-CUL3:RBX1:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Rattus norvegicus)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
RBX1:CUL3:BTB [cytosol] (Rattus norvegicus)
BTB proteins [cytosol] (Rattus norvegicus)
Klhl21 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D4A2K4
Gene Names
Klhl21
Reference Genes
BioGPS Gene:313743 Klhl21
ENSEMBL:ENSRNOG00000003334
ENSEMBL:ENSRNOG00000003334.6 Klhl21
ENSEMBL:ENSRNOG00055015527
ENSEMBL:ENSRNOG00060003558
ENSEMBL:ENSRNOG00065009694
KEGG Gene (Rattus norvegicus):313743 Klhl21
Monarch:313743 Klhl21
NCBI Gene:313743 Klhl21
UCSC:D4A2K4 Klhl21
Reference Transcript
RefSeq:NM_001107996.1 Klhl21
Other Identifiers
10874240
1371995_at
17804503
313743
5664846
5823784
6152517
6164797
6246538
6253769
6508704
6555958
6712920
6714190
6745829
A_43_P20207
A_64_P041802
A_64_P041807
GE1174539
GE1184226
GO:0000910
GO:0003824
GO:0004842
GO:0005515
GO:0005827
GO:0005856
GO:0016567
GO:0016740
GO:0031463
GO:0032465
GO:0035853
GO:0036211
GO:0043226
GO:0097602
GO:0140096
ILMN_1650312
PH_rn_0007573
rc_AI102706_at
Participates
as a member of
BTB proteins [cytosol] (Rattus norvegicus)
Inferred From
KLHL21 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001101466.1
Ensembl
ENSRNOT00000004508
,
ENSRNOP00000004508
,
ENSRNOG00000003334
PRO
D4A2K4
RGD
1305863
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