Reactome | CLN3 [nucleoplasm]

CLN3 [nucleoplasm]

Stable Identifier

R-SCE-113832

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

CCND1, P13365

Locations in the PathwayBrowser

Expand all

Cell Cycle (Saccharomyces cerevisiae)

- Cell Cycle, Mitotic (Saccharomyces cerevisiae)
  - Mitotic G1 phase and G1/S transition (Saccharomyces cerevisiae)
    - G1 Phase (Saccharomyces cerevisiae)
      - Cyclin D associated events in G1 (Saccharomyces cerevisiae)
        
        CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Saccharomyces cerevisiae)
        
        CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK4:CCND [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK4:CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK6:CCND [nucleoplasm] (Saccharomyces cerevisiae)
        
        Cyclin D1:Cdk6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T172-CDK4:CCND [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T172-CDK4:CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T177-CDK6:CCND [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T177-CDK6:CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Drug-mediated inhibition of CDK4/CDK6 activity (Saccharomyces cerevisiae)
        
        CDK4 inhibitors bind CDK4 (Saccharomyces cerevisiae)
        
        p-T172-CDK4:CCND [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T172-CDK4:CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T172-CDK4:CCND:CDK4 inhibitors [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T172-CDK4:CCND1:CDK4 inhibitors (CCND1) [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T172-CDK4:CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK6 inhibitors bind CDK6 (Saccharomyces cerevisiae)
        
        p-T177-CDK6:CCND [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T177-CDK6:CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T177-CDK6:CCND:CDK6 inhibitors [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T177-CDK6:CCND1:CDK6 inhibitors (CCND1) [nucleoplasm] (Saccharomyces cerevisiae)
        
        p-T177-CDK6:CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Saccharomyces cerevisiae)
        
        CDK4,CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); CDK4,CDK6:CCND; (CDK4,CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK4:CCND [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK4:CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK6:CCND [nucleoplasm] (Saccharomyces cerevisiae)
        
        Cyclin D1:Cdk6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CLN3 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P13365

Gene Names

CLN3

Reference Genes

BioGPS Gene:851191 CLN3

ENSEMBL:YAL040C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YAL040C CLN3

Monarch:851191 CLN3

NCBI Gene:851191 CLN3

SGD:YAL040C

Reference Transcript

RefSeq:NM_001178185.1 CLN3

Other Identifiers

11369_at

1776614_at

851191

GO:0000079

GO:0000083

GO:0000278

GO:0003674

GO:0005575

GO:0005634

GO:0006468

GO:0007033

GO:0007089

GO:0008150

GO:0008361

GO:0016538

GO:0030234

GO:0031399

GO:0042144

GO:0048284

GO:0051301

GO:0051726

Participates

as a member of

Homologues of CCND1 [nucleoplasm] (Saccharomyces cerevisiae)

Other forms of this molecule

CLN3 [nucleoplasm]

phospho-CLN3 [cytosol]

phospho-CLN3 [nucleoplasm]

CLN3 [cytosol]

CLN3 [nucleoplasm]

CLN3 [cytosol]

CLN3 [nucleoplasm]

CLN3 [cytosol]

CLN3 [nucleoplasm]

Inferred From

CCND1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_009360.1

OpenTargets

ENSG00000188603

PRO

P13365

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00546	11	phospho-CDC28 [nucleoplasm] (R-SCE-187967) CDC28 [nucleoplasm] (R-SCE-68365) CDC28 [cytosol] (R-SCE-157440) phospho-CDC28 [nucleoplasm] (R-SCE-69628) phospho-CDC28 [nucleoplasm] (R-SCE-113830) CDC28 [nucleoplasm] (R-SCE-141283) CDC28 [nucleoplasm] (R-SCE-113843) CDC28 [cytosol] (R-SCE-68336) CDC28 [cytosol] (R-SCE-68330) phospho-CDC28 [nucleoplasm] (R-SCE-68370) phospho-CDC28 [nucleoplasm] (R-SCE-187905)	0.826	6

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