Reactome | GNA14 [plasma membrane]

GNA14 [plasma membrane]

Stable Identifier

R-SCE-167453

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

plasma membrane

Synonyms

P08539

Locations in the PathwayBrowser

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Hemostasis (Saccharomyces cerevisiae)

- Platelet activation, signaling and aggregation (Saccharomyces cerevisiae)
  - Signal amplification (Saccharomyces cerevisiae)
    - ADP signalling through P2Y purinoceptor 1 (Saccharomyces cerevisiae)
      - P2Y purinoceptor 1 activates MAP kinase p38 alpha (Saccharomyces cerevisiae)
        
        G protein alpha:GTP complex [plasma membrane] (Saccharomyces cerevisiae)
        
        G-protein alpha (q/11/14/15) [plasma membrane] (Saccharomyces cerevisiae)
        
        GNA14 [plasma membrane] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P08539

Reference Genes

BioGPS Gene:856394

ENSEMBL:YHR005C

KEGG:sce:YHR005C

Monarch:856394

NCBI Gene:856394

SGD:YHR005C

UCSC:P08539

Reference Transcript

RefSeq:NM_001179135.1

Other Identifiers

1769776_at

4522_at

856394

GO:0000166

GO:0000742

GO:0000743

GO:0000747

GO:0000750

GO:0000754

GO:0001664

GO:0003674

GO:0003924

GO:0004871

GO:0005515

GO:0005525

GO:0005575

GO:0005737

GO:0005768

GO:0005829

GO:0005834

GO:0005886

GO:0006109

GO:0006997

GO:0007165

GO:0007186

GO:0007188

GO:0008150

GO:0010008

GO:0012505

GO:0015031

GO:0016020

GO:0016787

GO:0019001

GO:0019236

GO:0023052

GO:0031410

GO:0031681

GO:0031683

GO:0042221

GO:0043167

GO:0046872

GO:0048017

GO:0048284

GO:0051049

GO:0051169

GO:0071701

Participates

as a candidate of

G(q) alpha 11,14,15,Q [plasma membrane] (Saccharomyces cerevisiae)

as a member of

G-protein alpha (q/11/14/15) [plasma membrane] (Saccharomyces cerevisiae)

Other forms of this molecule

GNA13 [plasma membrane]

GNAL [plasma membrane]

GNA15 [plasma membrane]

GNA11 [plasma membrane]

Inferred From

GNA14 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_011868.1

ENSEMBL

YHR005C, YHR005C_mRNA, YHR005C

PRO

P08539

PDB

7AD3

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P18851	3	STE4 [cytosol] (R-SCE-6814200) STE4 [cytosol] (R-SCE-6814203) STE4 [cytosol] (R-SCE-6814204)	0.912	9
UniProt:P11972	12	SST2 [plasma membrane] (R-SCE-921136) SST2 [plasma membrane] (R-SCE-939769) SST2 [plasma membrane] (R-SCE-939776) SST2 [plasma membrane] (R-SCE-939779) SST2 [plasma membrane] (R-SCE-8849226) SST2 [plasma membrane] (R-SCE-939799) SST2 [plasma membrane] (R-SCE-8849407) SST2 [plasma membrane] (R-SCE-8849408) SST2 [plasma membrane] (R-SCE-921129) SST2 [plasma membrane] (R-SCE-939787) SST2 [plasma membrane] (R-SCE-921135) SST2 [plasma membrane] (R-SCE-939775)	0.641	3
UniProt:P22543	2	VPS34 [phagocytic vesicle membrane] (R-SCE-6798182) VPS34 [cytosol] (R-SCE-188011)	0.556	3
UniProt:P16892	20	phospho-p-T185,Y187-MAPK1 [nucleoplasm] (R-SCE-112354-2) phospho-p-T202,Y204-MAPK3 [nucleoplasm] (R-SCE-112359-2) phospho-p-T202,Y204-MAPK3 [cytosol] (R-SCE-109842-2) phospho-p-T185,Y187-MAPK1 [cytosol] (R-SCE-109853-2) MAPK1 [cytosol] (R-SCE-59282-2) MAPK3 [cytosol] (R-SCE-59284-2) phospho-p-T218,Y221-MAPK7 [nucleoplasm] (R-SCE-198738) phospho-p-T218,Y221-MAPK7 [cytosol] (R-SCE-198721) MAPK7 [nucleoplasm] (R-SCE-199961) MAPK3 [nucleoplasm] (R-SCE-73724-2) MAPK1 [nucleoplasm] (R-SCE-199960-2) phospho-p-T185-MAPK1 [cytosol] (R-SCE-9635773-2) phospho-p-T202-MAPK3 [cytosol] (R-SCE-9635775-2) NLK [cytosol] (R-SCE-4411330-2) phospho-p-T298-NLK [cytosol] (R-SCE-4411398-2) phospho-p-T298-NLK [nucleoplasm] (R-SCE-4411376-2) MAPK1 [ficolin-1-rich granule lumen] (R-SCE-6800964-2) MAPK1 [extracellular region] (R-SCE-6806250-2) MAPK1 [azurophil granule lumen] (R-SCE-6799225-2) phospho-p-3S,T MAPK6 [nucleoplasm] (R-SCE-5692665-2)	0.544	2
UniProt:P22219	2	PIK3R4 [phagocytic vesicle membrane] (R-SCE-6798171) PIK3R4 [cytosol] (R-SCE-188010)	0.524	2