Reactome | SKP1 [cytosol]

SKP1 [cytosol]

Stable Identifier

R-SCE-174150

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

SKP1, P52286

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - Neddylation (Saccharomyces cerevisiae)
    - AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Saccharomyces cerevisiae)
      - NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Saccharomyces cerevisiae)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Saccharomyces cerevisiae)
        
        SCF E3 ubiquitin ligase [cytosol] (Saccharomyces cerevisiae)
        
        SKP1 [cytosol] (Saccharomyces cerevisiae)
      - NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Saccharomyces cerevisiae)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Saccharomyces cerevisiae)
        
        SKP1 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P52286

Gene Names

SKP1

Reference Genes

BioGPS Gene:851928 SKP1

ENSEMBL:YDR328C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDR328C SKP1

Monarch:851928 SKP1

NCBI Gene:851928 SKP1

SGD:YDR328C

Reference Transcript

RefSeq:NM_001180636.3 SKP1

Other Identifiers

1778975_at

6160_at

851928

GO:0000082

GO:0000086

GO:0000278

GO:0000776

GO:0000777

GO:0000921

GO:0002181

GO:0003674

GO:0003677

GO:0003688

GO:0005575

GO:0005634

GO:0005694

GO:0005737

GO:0006417

GO:0006511

GO:0006873

GO:0007010

GO:0007035

GO:0007096

GO:0008150

GO:0010458

GO:0019005

GO:0031146

GO:0031518

GO:0033043

GO:0042787

GO:0043254

GO:0043291

GO:0043623

GO:0045116

GO:0048285

GO:0051382

GO:0051603

GO:0051726

GO:0070647

GO:0070925

GO:2000766

Participates

as a component of

Other forms of this molecule

SKP1 [nucleoplasm]

Inferred From

SKP1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_010615.3

OpenTargets

ENSG00000113558

PRO

P52286

PDB

1NEX, 6FE8, 6GSA, 5AN3, 3V7D, 3MKS, 6GYP, 6GYU, 6GYS, 6F07

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08446	1	SGT1 [cytosol] (R-SCE-874107)	0.833	8
UniProt:Q03919	8	RUB1 [cytosol] (R-SCE-8951739) RUB1 [nucleoplasm] (R-SCE-8952504) RUB1 [cytosol] (R-SCE-6782654) RUB1 [cytosol] (R-SCE-5690794) RUB1 [cytosol] (R-SCE-8951647) RUB1 [cytosol] (R-SCE-8952534) RUB1 [cytosol] (R-SCE-4419895) RUB1 [cytosol] (R-SCE-416969)	0.547	2
UniProt:P32324 EFT1	11	diphthine EFT1 [cytosol] (R-SCE-5367015) EFT2 [cytosol] (R-SCE-8932237) Me-diphthine EFT1 [cytosol] (R-SCE-5367013) EFT2 [cytosol] (R-SCE-156901) EFT2 [cytosol] (R-SCE-5358501) EFT2 [cytosol] (R-SCE-5358472) EFT2 [secretory granule lumen] (R-SCE-6801504) EFT2 [extracellular region] (R-SCE-6806499) EFT2 [ficolin-1-rich granule lumen] (R-SCE-6801513) EFT2 [cytosol] (R-SCE-5358478) EFT2 [cytosol] (R-SCE-5367025)	0.499	2

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