Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
VPS34 [cytosol]
Stable Identifier
R-SCE-188011
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
PIK3C3, P22543
Locations in the PathwayBrowser
Expand all
Autophagy (Saccharomyces cerevisiae)
Macroautophagy (Saccharomyces cerevisiae)
Autophagosome maturation (Saccharomyces cerevisiae)
UVRAG complex [cytosol] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
Beclin-1 complex phosphorylates PtdIns (Saccharomyces cerevisiae)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
Beclin-1 complex translocates to the ER (Saccharomyces cerevisiae)
BECN1 complex [cytosol] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
Beclin-1 complex [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
The phagophore extends from the PIP3-enriched structure (Saccharomyces cerevisiae)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [phagophore assembly site membrane] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
ULK1 phosphorylates Beclin-1 (Saccharomyces cerevisiae)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
Beclin-1 complex [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Phospholipid metabolism (Saccharomyces cerevisiae)
PI Metabolism (Saccharomyces cerevisiae)
Synthesis of PIPs at the Golgi membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Saccharomyces cerevisiae)
PIK3C3:Mn2+:PIK3R4:Mn2+ [cytosol] (Saccharomyces cerevisiae)
PIK3C3:Mn2+ [cytosol] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
Synthesis of PIPs at the early endosome membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Saccharomyces cerevisiae)
PIK3C3:Mn2+:PIK3R4:Mn2+ [cytosol] (Saccharomyces cerevisiae)
PIK3C3:Mn2+ [cytosol] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
Synthesis of PIPs at the late endosome membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Saccharomyces cerevisiae)
PIK3C3:Mn2+:PIK3R4:Mn2+ [cytosol] (Saccharomyces cerevisiae)
PIK3C3:Mn2+ [cytosol] (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Saccharomyces cerevisiae)
Signaling by Rho GTPases (Saccharomyces cerevisiae)
RHO GTPase Effectors (Saccharomyces cerevisiae)
RHO GTPases Activate NADPH Oxidases (Saccharomyces cerevisiae)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Saccharomyces cerevisiae)
VPS34 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P22543
Gene Names
VPS34
Reference Genes
BioGPS Gene:850941 VPS34
ENSEMBL:YLR240W
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YLR240W VPS34
Monarch:850941 VPS34
NCBI Gene:850941 VPS34
SGD:YLR240W
Reference Transcript
RefSeq:NM_001182127.1 VPS34
Other Identifiers
10088_at
1769875_at
850941
GO:0000045
GO:0000139
GO:0000166
GO:0000329
GO:0000407
GO:0000425
GO:0003674
GO:0004672
GO:0005515
GO:0005524
GO:0005575
GO:0005737
GO:0005768
GO:0005773
GO:0005777
GO:0005794
GO:0005829
GO:0006354
GO:0006366
GO:0006468
GO:0006629
GO:0006897
GO:0006914
GO:0006970
GO:0007033
GO:0008150
GO:0009651
GO:0010008
GO:0012505
GO:0015031
GO:0016020
GO:0016197
GO:0016236
GO:0016301
GO:0016303
GO:0016310
GO:0016740
GO:0016773
GO:0023052
GO:0030242
GO:0031410
GO:0032968
GO:0034045
GO:0034271
GO:0034272
GO:0036092
GO:0043167
GO:0045324
GO:0046854
GO:0048015
GO:0070925
GO:0071561
GO:0072593
Participates
as a component of
PI3K class III [cytosol] (Saccharomyces cerevisiae)
PIK3C3:Mn2+ [cytosol] (Saccharomyces cerevisiae)
UVRAG complex [cytosol] (Saccharomyces cerevisiae)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [phagophore assembly site membrane] (Saccharomyces cerevisiae)
ATG14:PIK3C3:PIK3R4:p-S15-BECN1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
Beclin-1 complex [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
BECN1 complex [cytosol] (Saccharomyces cerevisiae)
Other forms of this molecule
VPS34 [phagocytic vesicle membrane]
Inferred From
PIK3C3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_013341.1
PRO
P22543
PDB
5DFZ
,
5KC2
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08539
5
GNA13 [plasma membrane]
(R-SCE-167451)
GNAL [plasma membrane]
(R-SCE-170657)
GNA14 [plasma membrane]
(R-SCE-167453)
GNA15 [plasma membrane]
(R-SCE-167450)
GNA11 [plasma membrane]
(R-SCE-167446)
0.556
3
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text