Reactome | RPD3 [nucleoplasm]

RPD3 [nucleoplasm]

Stable Identifier

R-SCE-205021

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

HDAC1, P32561

Locations in the PathwayBrowser

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Chromatin organization (Saccharomyces cerevisiae)

- Chromatin modifying enzymes (Saccharomyces cerevisiae)
  - HDACs deacetylate histones (Saccharomyces cerevisiae)
    - HDAC1:2-containing complex binds HDAC2 Inhibitors (Saccharomyces cerevisiae)
      - HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Saccharomyces cerevisiae)
        
        Sin3A complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        Sin3a core complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        HDAC1:HDAC2 [nucleoplasm] (Saccharomyces cerevisiae)
        
        RPD3 [nucleoplasm] (Saccharomyces cerevisiae)
      - Sin3A complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        Sin3a core complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        HDAC1:HDAC2 [nucleoplasm] (Saccharomyces cerevisiae)
        
        RPD3 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P32561

Gene Names

RPD3

Reference Genes

BioGPS Gene:855386 RPD3

ENSEMBL:YNL330C

KEGG:sce:YNL330C RPD3

Monarch:855386 RPD3

NCBI Gene:855386 RPD3

SGD:YNL330C

UCSC:P32561 RPD3

Reference Transcript

RefSeq:NM_001183168.1 RPD3

Other Identifiers

855386

GO:0000082

GO:0000083

GO:0000086

GO:0000117

GO:0000118

GO:0000122

GO:0001302

GO:0003674

GO:0003713

GO:0003714

GO:0004407

GO:0005515

GO:0005575

GO:0005634

GO:0005737

GO:0006325

GO:0006334

GO:0006354

GO:0006355

GO:0006357

GO:0006368

GO:0006979

GO:0006995

GO:0008150

GO:0008270

GO:0009408

GO:0010557

GO:0016239

GO:0016479

GO:0016787

GO:0030174

GO:0031507

GO:0031939

GO:0032041

GO:0032221

GO:0033043

GO:0033698

GO:0034399

GO:0034503

GO:0034605

GO:0042594

GO:0043167

GO:0044804

GO:0045128

GO:0045944

GO:0051038

GO:0051052

GO:0051321

GO:0051726

GO:0061186

GO:0061188

GO:0061587

GO:0070210

GO:0070211

GO:0070550

GO:0070822

GO:0070932

GO:0070933

GO:0141221

Participates

as an input of

SUMOylation of HDAC1 with SUMO1 (Saccharomyces cerevisiae)

as a component of

Other forms of this molecule

RPD3 [nucleoplasm]

Inferred From

HDAC1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_014069.1

ENSEMBL

YNL330C, YNL330C_mRNA, YNL330C

PRO

P32561

PDB

8GA8, 8HPO, 7YI3, 8KD7, 8W9F, 7YI5, 8IHT, 8KD5, 8HY0, 8IHN, 7YI4, 8KD6, 8HXX, 8W9D, 8KD3, 8KD2, 8HXY, 7YI2, 7YI0, 8JHO, 8KD4, 8W9C, 8W9E, 8TOF, 8KC7

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22579	3	SIN3 [nucleoplasm] (R-SCE-349685) SIN3 [nucleoplasm] (R-SCE-351657) SIN3 [nucleoplasm] (R-SCE-4086071)	0.905	28
UniProt:P38255 RXT2			0.888	12
UniProt:Q03010	1	UME1 [nucleoplasm] (R-SCE-212223-2)	0.848	11
UniProt:Q04779 RCO1			0.848	13
UniProt:Q08923 CTI6			0.848	10
UniProt:P50947	3	PHO23 [nucleoplasm] (R-SCE-4086075-2) PHO23 [nucleoplasm] (R-SCE-3215167-2) PHO23 [nucleoplasm] (R-SCE-3215169-2)	0.848	10
UniProt:P40505	2	SDS3 [nucleoplasm] (R-SCE-6782790-2) SDS3 [nucleoplasm] (R-SCE-351696-2)	0.802	5
UniProt:Q12432 EAF3			0.802	12
UniProt:P34233 ASH1			0.775	5
UniProt:P38429	2	SAP30 [nucleoplasm] (R-SCE-351693) SAP30 [nucleoplasm] (R-SCE-351698)	0.744	8
UniProt:Q07458 RXT3			0.725	4
UniProt:P31385	3	DEP1 [nucleoplasm] (R-SCE-6782790) DEP1 [nucleoplasm] (R-SCE-351696) DEP1 [nucleoplasm] (R-SCE-4650034)	0.725	4
UniProt:P14922	2	CYC8 [nucleoplasm] (R-SCE-4754224) CYC8 [nucleoplasm] (R-SCE-1629833)	0.697	6
UniProt:Q03214 ECM5			0.597	5
UniProt:P16649 TUP1			0.589	2
UniProt:Q08032	1	CDC45 [nucleoplasm] (R-SCE-68563)	0.527	2
UniProt:Q03213 HOT1			0.524	3
UniProt:P53691	4	CPR6 [ficolin-1-rich granule lumen] (R-SCE-6801393) CPR6 [extracellular region] (R-SCE-6806493) CPR6 [secretory granule lumen] (R-SCE-6801369) CPR6 [nucleoplasm] (R-SCE-6781959)	0.508	2
UniProt:P47103	1	CPR7 [nucleoplasm] (R-SCE-8939168)	0.508	2
UniProt:P53127 SNT2			0.462	3