Reactome | HPC2 [nucleoplasm]

HPC2 [nucleoplasm]

Stable Identifier

R-SCE-2532791

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

UBN1, Q01448

Locations in the PathwayBrowser for interactor UniProt:P32480 HIR2

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Cellular responses to stimuli (Saccharomyces cerevisiae)

- Cellular responses to stress (Saccharomyces cerevisiae)
  - Cellular Senescence (Saccharomyces cerevisiae)
    - DNA Damage/Telomere Stress Induced Senescence (Saccharomyces cerevisiae)
      - Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Saccharomyces cerevisiae)
        
        Initiation of SAHF formation (Saccharomyces cerevisiae)
        
        HPC2 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:Q01448

Gene Names

HPC2

Reference Genes

BioGPS Gene:852516 HPC2

ENSEMBL:YBR215W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YBR215W HPC2

Monarch:852516 HPC2

NCBI Gene:852516 HPC2

SGD:YBR215W

Reference Transcript

RefSeq:NM_001178563.3 HPC2

Other Identifiers

1769925_at

7125_at

852516

GO:0000083

GO:0000278

GO:0000417

GO:0003674

GO:0003677

GO:0003682

GO:0005515

GO:0005575

GO:0005634

GO:0005694

GO:0006325

GO:0006334

GO:0006336

GO:0006354

GO:0006357

GO:0006366

GO:0006368

GO:0008150

GO:0016569

GO:0031491

GO:1905268

Participates

as an input of

Initiation of SAHF formation (Saccharomyces cerevisiae)

as a component of

HIRA:ASF1A:UBN1:CABIN1 [nucleoplasm] (Saccharomyces cerevisiae)

Inferred From

UBN1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_009774.4

PRO

Q01448

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32479	1	HIR1 [nucleoplasm] (R-SCE-2532790)	0.839	9
UniProt:P32447	1	ASF1 [nucleoplasm] (R-SCE-417169)	0.69	11
UniProt:P32480 HIR2			0.669	5
UniProt:P47171	1	HIR3 [nucleoplasm] (R-SCE-3878125)	0.669	5

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