Reactome | ITSN1 [cytosol]

ITSN1 [cytosol]

Stable Identifier

R-SCE-3006481-2

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

P34216

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Saccharomyces cerevisiae)

- Membrane Trafficking (Saccharomyces cerevisiae)
  - Clathrin-mediated endocytosis (Saccharomyces cerevisiae)
    - AAK1 phosphorylates AP-2 mu subunit at T156 (Saccharomyces cerevisiae)
      - PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Saccharomyces cerevisiae)
        
        PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Saccharomyces cerevisiae)
        
        ITSNs [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of ITSN1 [cytosol] (Saccharomyces cerevisiae)
        
        ITSN1 [cytosol] (Saccharomyces cerevisiae)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Saccharomyces cerevisiae)
        
        ITSNs [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of ITSN1 [cytosol] (Saccharomyces cerevisiae)
        
        ITSN1 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P34216

Reference Genes

BioGPS Gene:852233

ENSEMBL:YBL047C

KEGG:sce:YBL047C

Monarch:852233

NCBI Gene:852233

SGD:YBL047C

UCSC:P34216

Reference Transcript

RefSeq:NM_001178287.1

Other Identifiers

1777838_at

7405_at

852233

GO:0000910

GO:0003674

GO:0005509

GO:0005515

GO:0005575

GO:0005737

GO:0005856

GO:0005886

GO:0005933

GO:0005934

GO:0005935

GO:0005938

GO:0006897

GO:0007010

GO:0008150

GO:0016020

GO:0016197

GO:0023052

GO:0030427

GO:0030479

GO:0030968

GO:0032182

GO:0032467

GO:0032880

GO:0042221

GO:0043130

GO:0043167

GO:0043332

GO:0044396

GO:0046872

GO:0051726

Participates

as a member of

Homologues of ITSN1 [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

REPS1 [cytosol]

ITSN2 [cytosol]

EPS15 [cytosol]

Inferred From

ITSN1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

YBL047C_mRNA, YBL047C, YBL047C

PRO

P34216

PDB

2G3Q, 6WY6

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29295	3	CSNK1D [nucleoplasm] (R-SCE-421305) CSNK1E [nucleoplasm] (R-SCE-421306) CSNK1D [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-SCE-5685717)	0.527	4
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [cytosol] (R-SCE-5251948-3)	0.527	2